GPATCH8-KRT25 Fusion FISH Probe
The GPATCH8-KRT25 Fusion FISH Probe is used to confirm a fusion of the GPATCH8 and KRT25 genes. The fusion of the GPATCH8 and KRT25 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| GPATCH8-KRT25-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| GPATCH8-KRT25-20-RERE | 20 (40 μL) | 200 μL |
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| GPATCH8-KRT25-20-REOR | 20 (40 μL) | 200 μL |
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| GPATCH8-KRT25-20-REGO | 20 (40 μL) | 200 μL |
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| GPATCH8-KRT25-20-REGR | 20 (40 μL) | 200 μL |
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| GPATCH8-KRT25-20-REAQ | 20 (40 μL) | 200 μL |
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| GPATCH8-KRT25-20-ORRE | 20 (40 μL) | 200 μL |
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| GPATCH8-KRT25-20-OROR | 20 (40 μL) | 200 μL |
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| GPATCH8-KRT25-20-ORGO | 20 (40 μL) | 200 μL |
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| GPATCH8-KRT25-20-ORAQ | 20 (40 μL) | 200 μL |
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| GPATCH8-KRT25-20-GORE | 20 (40 μL) | 200 μL |
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| GPATCH8-KRT25-20-GOOR | 20 (40 μL) | 200 μL |
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| GPATCH8-KRT25-20-GOGO | 20 (40 μL) | 200 μL |
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| GPATCH8-KRT25-20-GOGR | 20 (40 μL) | 200 μL |
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| GPATCH8-KRT25-20-GOAQ | 20 (40 μL) | 200 μL |
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| GPATCH8-KRT25-20-GRRE | 20 (40 μL) | 200 μL |
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| GPATCH8-KRT25-20-GROR | 20 (40 μL) | 200 μL |
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| GPATCH8-KRT25-20-GRGO | 20 (40 μL) | 200 μL |
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| GPATCH8-KRT25-20-GRGR | 20 (40 μL) | 200 μL |
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| GPATCH8-KRT25-20-GRAQ | 20 (40 μL) | 200 μL |
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| GPATCH8-KRT25-20-AQRE | 20 (40 μL) | 200 μL |
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| GPATCH8-KRT25-20-AQOR | 20 (40 μL) | 200 μL |
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| GPATCH8-KRT25-20-AQGO | 20 (40 μL) | 200 μL |
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| GPATCH8-KRT25-20-AQGR | 20 (40 μL) | 200 μL |
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| GPATCH8-KRT25-20-AQAQ | 20 (40 μL) | 200 μL |
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GPATCH8 Gene Summary
The protein encoded by this gene contains an RNA-processing domain, a zinc finger domain, a lysine-rich region and a serine-rich region. A mutation in the serine-rich region of the protein is thought to be associated with hyperuricemia (PMID: 21594610). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2015]
Gene Name: G-patch Domain Containing 8
Chromosome: CHR17: 42472644 -42580957
Locus: 17q21.31
KRT25 Gene Summary
This gene encodes a member of the type I (acidic) keratin family, which belongs to the superfamily of intermediate filament (IF) proteins. Keratins are heteropolymeric structural proteins which form the intermediate filament. These filaments, along with actin microfilaments and microtubules, compose the cytoskeleton of epithelial cells. The type I keratin genes are clustered in a region of chromosome 17q12-q21. [provided by RefSeq, Jul 2009]
Gene Name: Keratin 25
Chromosome: CHR17: 38904272 -38911584
Locus: 17q21.2
Gene Diseases
The GPATCH8 KRT25 Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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