GPBP1L1-PVR Fusion FISH Probe
The GPBP1L1-PVR Fusion FISH Probe is used to confirm a fusion of the GPBP1L1 and PVR genes. The fusion of the GPBP1L1 and PVR genes has been associated with Brain Lower Grade Glioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| GPBP1L1-PVR-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| GPBP1L1-PVR-20-RERE | 20 (40 μL) | 200 μL |
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| GPBP1L1-PVR-20-REOR | 20 (40 μL) | 200 μL |
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| GPBP1L1-PVR-20-REGO | 20 (40 μL) | 200 μL |
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| GPBP1L1-PVR-20-REGR | 20 (40 μL) | 200 μL |
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| GPBP1L1-PVR-20-REAQ | 20 (40 μL) | 200 μL |
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| GPBP1L1-PVR-20-ORRE | 20 (40 μL) | 200 μL |
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| GPBP1L1-PVR-20-OROR | 20 (40 μL) | 200 μL |
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| GPBP1L1-PVR-20-ORGO | 20 (40 μL) | 200 μL |
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| GPBP1L1-PVR-20-ORAQ | 20 (40 μL) | 200 μL |
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| GPBP1L1-PVR-20-GORE | 20 (40 μL) | 200 μL |
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| GPBP1L1-PVR-20-GOOR | 20 (40 μL) | 200 μL |
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| GPBP1L1-PVR-20-GOGO | 20 (40 μL) | 200 μL |
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| GPBP1L1-PVR-20-GOGR | 20 (40 μL) | 200 μL |
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| GPBP1L1-PVR-20-GOAQ | 20 (40 μL) | 200 μL |
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| GPBP1L1-PVR-20-GRRE | 20 (40 μL) | 200 μL |
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| GPBP1L1-PVR-20-GROR | 20 (40 μL) | 200 μL |
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| GPBP1L1-PVR-20-GRGO | 20 (40 μL) | 200 μL |
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| GPBP1L1-PVR-20-GRGR | 20 (40 μL) | 200 μL |
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| GPBP1L1-PVR-20-GRAQ | 20 (40 μL) | 200 μL |
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| GPBP1L1-PVR-20-AQRE | 20 (40 μL) | 200 μL |
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| GPBP1L1-PVR-20-AQOR | 20 (40 μL) | 200 μL |
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| GPBP1L1-PVR-20-AQGO | 20 (40 μL) | 200 μL |
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| GPBP1L1-PVR-20-AQGR | 20 (40 μL) | 200 μL |
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| GPBP1L1-PVR-20-AQAQ | 20 (40 μL) | 200 μL |
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PVR Gene Summary
The protein encoded by this gene is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. The external domain mediates cell attachment to the extracellular matrix molecule vitronectin, while its intracellular domain interacts with the dynein light chain Tctex-1/DYNLT1. The gene is specific to the primate lineage, and serves as a cellular receptor for poliovirus in the first step of poliovirus replication. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]
Gene Name: Poliovirus Receptor
Chromosome: CHR19: 45147097 -45169428
Locus: 19q13.31
GPBP1L1 Gene Summary
The GC-rich Promoter Binding Protein 1 Like 1 (GPBP1L1) gene is located on chr1 :46092975-46152302 at 1p34.1.
Gene Name: GC-rich Promoter Binding Protein 1 Like 1
Chromosome: CHR1: 46092975 -46152302
Locus: 1p34.1
Gene Diseases
The GPBP1L1 PVR Fusion has been associated with the following diseases:
| Disease Name |
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| Brain Lower Grade Glioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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