GPHN-SLC8A3 Fusion FISH Probe
The GPHN-SLC8A3 Fusion FISH Probe is used to confirm a fusion of the GPHN and SLC8A3 genes. The fusion of the GPHN and SLC8A3 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| GPHN-SLC8A3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| GPHN-SLC8A3-20-RERE | 20 (40 μL) | 200 μL |
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| GPHN-SLC8A3-20-REOR | 20 (40 μL) | 200 μL |
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| GPHN-SLC8A3-20-REGO | 20 (40 μL) | 200 μL |
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| GPHN-SLC8A3-20-REGR | 20 (40 μL) | 200 μL |
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| GPHN-SLC8A3-20-REAQ | 20 (40 μL) | 200 μL |
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| GPHN-SLC8A3-20-ORRE | 20 (40 μL) | 200 μL |
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| GPHN-SLC8A3-20-OROR | 20 (40 μL) | 200 μL |
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| GPHN-SLC8A3-20-ORGO | 20 (40 μL) | 200 μL |
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| GPHN-SLC8A3-20-ORAQ | 20 (40 μL) | 200 μL |
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| GPHN-SLC8A3-20-GORE | 20 (40 μL) | 200 μL |
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| GPHN-SLC8A3-20-GOOR | 20 (40 μL) | 200 μL |
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| GPHN-SLC8A3-20-GOGO | 20 (40 μL) | 200 μL |
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| GPHN-SLC8A3-20-GOGR | 20 (40 μL) | 200 μL |
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| GPHN-SLC8A3-20-GOAQ | 20 (40 μL) | 200 μL |
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| GPHN-SLC8A3-20-GRRE | 20 (40 μL) | 200 μL |
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| GPHN-SLC8A3-20-GROR | 20 (40 μL) | 200 μL |
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| GPHN-SLC8A3-20-GRGO | 20 (40 μL) | 200 μL |
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| GPHN-SLC8A3-20-GRGR | 20 (40 μL) | 200 μL |
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| GPHN-SLC8A3-20-GRAQ | 20 (40 μL) | 200 μL |
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| GPHN-SLC8A3-20-AQRE | 20 (40 μL) | 200 μL |
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| GPHN-SLC8A3-20-AQOR | 20 (40 μL) | 200 μL |
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| GPHN-SLC8A3-20-AQGO | 20 (40 μL) | 200 μL |
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| GPHN-SLC8A3-20-AQGR | 20 (40 μL) | 200 μL |
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| GPHN-SLC8A3-20-AQAQ | 20 (40 μL) | 200 μL |
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SLC8A3 Gene Summary
This gene encodes a member of the sodium/calcium exchanger integral membrane protein family. Na+/Ca2+ exchange proteins are involved in maintaining Ca2+ homeostasis in a wide variety of cell types. The protein is regulated by intracellular calcium ions and is found in both the plasma membrane and intracellular organellar membranes, where exchange of Na+ for Ca2+ occurs in an electrogenic manner. Alternative splicing has been observed for this gene and multiple variants have been described. [provided by RefSeq, Aug 2013]
Gene Name: Solute Carrier Family 8 Member A3
Chromosome: CHR14: 70510933 -70655787
Locus: 14q24.2
GPHN Gene Summary
This gene encodes a neuronal assembly protein that anchors inhibitory neurotransmitter receptors to the postsynaptic cytoskeleton via high affinity binding to a receptor subunit domain and tubulin dimers. In nonneuronal tissues, the encoded protein is also required for molybdenum cofactor biosynthesis. Mutations in this gene may be associated with the neurological condition hyperplexia and also lead to molybdenum cofactor deficiency. Numerous alternatively spliced transcript variants encoding different isoforms have been described; however, the full-length nature of all transcript variants is not currently known. [provided by RefSeq, Jul 2008]
Gene Name: Gephyrin
Chromosome: CHR14: 66974124 -67648525
Locus: 14q23.3-q24.1
Gene Diseases
The GPHN SLC8A3 Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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