GPM6B-CHD1 Fusion FISH Probe
The GPM6B-CHD1 Fusion FISH Probe is used to confirm a fusion of the GPM6B and CHD1 genes. The fusion of the GPM6B and CHD1 genes has been associated with Brain Lower Grade Glioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| GPM6B-CHD1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| GPM6B-CHD1-20-RERE | 20 (40 μL) | 200 μL |
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| GPM6B-CHD1-20-REOR | 20 (40 μL) | 200 μL |
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| GPM6B-CHD1-20-REGO | 20 (40 μL) | 200 μL |
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| GPM6B-CHD1-20-REGR | 20 (40 μL) | 200 μL |
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| GPM6B-CHD1-20-REAQ | 20 (40 μL) | 200 μL |
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| GPM6B-CHD1-20-ORRE | 20 (40 μL) | 200 μL |
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| GPM6B-CHD1-20-OROR | 20 (40 μL) | 200 μL |
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| GPM6B-CHD1-20-ORGO | 20 (40 μL) | 200 μL |
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| GPM6B-CHD1-20-ORAQ | 20 (40 μL) | 200 μL |
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| GPM6B-CHD1-20-GORE | 20 (40 μL) | 200 μL |
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| GPM6B-CHD1-20-GOOR | 20 (40 μL) | 200 μL |
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| GPM6B-CHD1-20-GOGO | 20 (40 μL) | 200 μL |
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| GPM6B-CHD1-20-GOGR | 20 (40 μL) | 200 μL |
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| GPM6B-CHD1-20-GOAQ | 20 (40 μL) | 200 μL |
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| GPM6B-CHD1-20-GRRE | 20 (40 μL) | 200 μL |
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| GPM6B-CHD1-20-GROR | 20 (40 μL) | 200 μL |
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| GPM6B-CHD1-20-GRGO | 20 (40 μL) | 200 μL |
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| GPM6B-CHD1-20-GRGR | 20 (40 μL) | 200 μL |
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| GPM6B-CHD1-20-GRAQ | 20 (40 μL) | 200 μL |
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| GPM6B-CHD1-20-AQRE | 20 (40 μL) | 200 μL |
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| GPM6B-CHD1-20-AQOR | 20 (40 μL) | 200 μL |
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| GPM6B-CHD1-20-AQGO | 20 (40 μL) | 200 μL |
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| GPM6B-CHD1-20-AQGR | 20 (40 μL) | 200 μL |
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| GPM6B-CHD1-20-AQAQ | 20 (40 μL) | 200 μL |
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CHD1 Gene Summary
The CHD family of proteins is characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. CHD genes alter gene expression possibly by modification of chromatin structure thus altering access of the transcriptional apparatus to its chromosomal DNA template. [provided by RefSeq, Jul 2008]
Gene Name: Chromodomain Helicase DNA Binding Protein 1
Chromosome: CHR5: 98190907 -98262238
Locus: 5q15-q21.1
GPM6B Gene Summary
This gene encodes a membrane glycoprotein that belongs to the proteolipid protein family. Proteolipid protein family members are expressed in most brain regions and are thought to be involved in cellular housekeeping functions such as membrane trafficking and cell-to-cell communication. This protein may also be involved in osteoblast differentiation. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are located on chromosomes Y and 22. [provided by RefSeq, Jan 2016]
Gene Name: Glycoprotein M6B
Chromosome: CHRX: 13792092 -13956831
Locus: Xp22.2
Gene Diseases
The GPM6B CHD1 Fusion has been associated with the following diseases:
| Disease Name |
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| Brain Lower Grade Glioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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