GPR146-DTNBP1 Fusion FISH Probe
The GPR146-DTNBP1 Fusion FISH Probe is used to confirm a fusion of the GPR146 and DTNBP1 genes. The fusion of the GPR146 and DTNBP1 genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| GPR146-DTNBP1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| GPR146-DTNBP1-20-RERE | 20 (40 μL) | 200 μL |
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| GPR146-DTNBP1-20-REOR | 20 (40 μL) | 200 μL |
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| GPR146-DTNBP1-20-REGO | 20 (40 μL) | 200 μL |
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| GPR146-DTNBP1-20-REGR | 20 (40 μL) | 200 μL |
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| GPR146-DTNBP1-20-REAQ | 20 (40 μL) | 200 μL |
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| GPR146-DTNBP1-20-ORRE | 20 (40 μL) | 200 μL |
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| GPR146-DTNBP1-20-OROR | 20 (40 μL) | 200 μL |
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| GPR146-DTNBP1-20-ORGO | 20 (40 μL) | 200 μL |
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| GPR146-DTNBP1-20-ORAQ | 20 (40 μL) | 200 μL |
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| GPR146-DTNBP1-20-GORE | 20 (40 μL) | 200 μL |
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| GPR146-DTNBP1-20-GOOR | 20 (40 μL) | 200 μL |
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| GPR146-DTNBP1-20-GOGO | 20 (40 μL) | 200 μL |
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| GPR146-DTNBP1-20-GOGR | 20 (40 μL) | 200 μL |
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| GPR146-DTNBP1-20-GOAQ | 20 (40 μL) | 200 μL |
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| GPR146-DTNBP1-20-GRRE | 20 (40 μL) | 200 μL |
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| GPR146-DTNBP1-20-GROR | 20 (40 μL) | 200 μL |
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| GPR146-DTNBP1-20-GRGO | 20 (40 μL) | 200 μL |
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| GPR146-DTNBP1-20-GRGR | 20 (40 μL) | 200 μL |
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| GPR146-DTNBP1-20-GRAQ | 20 (40 μL) | 200 μL |
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| GPR146-DTNBP1-20-AQRE | 20 (40 μL) | 200 μL |
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| GPR146-DTNBP1-20-AQOR | 20 (40 μL) | 200 μL |
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| GPR146-DTNBP1-20-AQGO | 20 (40 μL) | 200 μL |
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| GPR146-DTNBP1-20-AQGR | 20 (40 μL) | 200 μL |
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| GPR146-DTNBP1-20-AQAQ | 20 (40 μL) | 200 μL |
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DTNBP1 Gene Summary
This gene encodes a protein that may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. A similar protein in mouse is a component of a protein complex termed biogenesis of lysosome-related organelles complex 1 (BLOC-1), and binds to alpha- and beta-dystrobrevins, which are components of the dystrophin-associated protein complex (DPC). Mutations in this gene are associated with Hermansky-Pudlak syndrome type 7. This gene may also be associated with schizophrenia. Multiple transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Dystrobrevin Binding Protein 1
Chromosome: CHR6: 15523031 -15663289
Locus: 6p22.3
GPR146 Gene Summary
The G Protein-coupled Receptor 146 (GPR146) gene is located on chr7 :1097140-1098897 at 7p22.3.
Gene Name: G Protein-coupled Receptor 146
Chromosome: CHR7: 1097140 -1098897
Locus: 7p22.3
Gene Diseases
The GPR146 DTNBP1 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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