GPRC5C-CLDN4 Fusion FISH Probe
The GPRC5C-CLDN4 Fusion FISH Probe is used to confirm a fusion of the GPRC5C and CLDN4 genes. The fusion of the GPRC5C and CLDN4 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| GPRC5C-CLDN4-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| GPRC5C-CLDN4-20-RERE | 20 (40 μL) | 200 μL |
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| GPRC5C-CLDN4-20-REOR | 20 (40 μL) | 200 μL |
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| GPRC5C-CLDN4-20-REGO | 20 (40 μL) | 200 μL |
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| GPRC5C-CLDN4-20-REGR | 20 (40 μL) | 200 μL |
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| GPRC5C-CLDN4-20-REAQ | 20 (40 μL) | 200 μL |
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| GPRC5C-CLDN4-20-ORRE | 20 (40 μL) | 200 μL |
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| GPRC5C-CLDN4-20-OROR | 20 (40 μL) | 200 μL |
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| GPRC5C-CLDN4-20-ORGO | 20 (40 μL) | 200 μL |
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| GPRC5C-CLDN4-20-ORAQ | 20 (40 μL) | 200 μL |
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| GPRC5C-CLDN4-20-GORE | 20 (40 μL) | 200 μL |
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| GPRC5C-CLDN4-20-GOOR | 20 (40 μL) | 200 μL |
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| GPRC5C-CLDN4-20-GOGO | 20 (40 μL) | 200 μL |
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| GPRC5C-CLDN4-20-GOGR | 20 (40 μL) | 200 μL |
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| GPRC5C-CLDN4-20-GOAQ | 20 (40 μL) | 200 μL |
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| GPRC5C-CLDN4-20-GRRE | 20 (40 μL) | 200 μL |
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| GPRC5C-CLDN4-20-GROR | 20 (40 μL) | 200 μL |
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| GPRC5C-CLDN4-20-GRGO | 20 (40 μL) | 200 μL |
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| GPRC5C-CLDN4-20-GRGR | 20 (40 μL) | 200 μL |
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| GPRC5C-CLDN4-20-GRAQ | 20 (40 μL) | 200 μL |
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| GPRC5C-CLDN4-20-AQRE | 20 (40 μL) | 200 μL |
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| GPRC5C-CLDN4-20-AQOR | 20 (40 μL) | 200 μL |
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| GPRC5C-CLDN4-20-AQGO | 20 (40 μL) | 200 μL |
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| GPRC5C-CLDN4-20-AQGR | 20 (40 μL) | 200 μL |
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| GPRC5C-CLDN4-20-AQAQ | 20 (40 μL) | 200 μL |
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CLDN4 Gene Summary
The protein encoded by this intronless gene belongs to the claudin family. Claudins are integral membrane proteins that are components of the epithelial cell tight junctions, which regulate movement of solutes and ions through the paracellular space. This protein is a high-affinity receptor for Clostridium perfringens enterotoxin (CPE) and may play a role in internal organ development and function during pre- and postnatal life. This gene is deleted in Williams-Beuren syndrome, a neurodevelopmental disorder affecting multiple systems. [provided by RefSeq, Sep 2013]
Gene Name: Claudin 4
Chromosome: CHR7: 73245192 -73247015
Locus: 7q11.23
GPRC5C Gene Summary
The protein encoded by this gene is a member of the type 3 G protein-coupled receptor family. Members of this superfamily are characterized by a signature 7-transmembrane domain motif. The specific function of this protein is unknown; however, this protein may mediate the cellular effects of retinoic acid on the G protein signal transduction cascade. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: G Protein-coupled Receptor Class C Group 5 Member C
Chromosome: CHR17: 72427666 -72443568
Locus: 17q25.1
Gene Diseases
The GPRC5C CLDN4 Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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