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HERC2-IGFBP6 Fusion FISH Probe

The HERC2-IGFBP6 Fusion FISH Probe is used to confirm a fusion of the HERC2 and IGFBP6 genes. The fusion of the HERC2 and IGFBP6 genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
HERC2-IGFBP6-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
HERC2-IGFBP6-20-RERE 20 (40 μL) 200 μL
HERC2-IGFBP6-20-REOR 20 (40 μL) 200 μL
HERC2-IGFBP6-20-REGO 20 (40 μL) 200 μL
HERC2-IGFBP6-20-REGR 20 (40 μL) 200 μL
HERC2-IGFBP6-20-REAQ 20 (40 μL) 200 μL
HERC2-IGFBP6-20-ORRE 20 (40 μL) 200 μL
HERC2-IGFBP6-20-OROR 20 (40 μL) 200 μL
HERC2-IGFBP6-20-ORGO 20 (40 μL) 200 μL
HERC2-IGFBP6-20-ORAQ 20 (40 μL) 200 μL
HERC2-IGFBP6-20-GORE 20 (40 μL) 200 μL
HERC2-IGFBP6-20-GOOR 20 (40 μL) 200 μL
HERC2-IGFBP6-20-GOGO 20 (40 μL) 200 μL
HERC2-IGFBP6-20-GOGR 20 (40 μL) 200 μL
HERC2-IGFBP6-20-GOAQ 20 (40 μL) 200 μL
HERC2-IGFBP6-20-GRRE 20 (40 μL) 200 μL
HERC2-IGFBP6-20-GROR 20 (40 μL) 200 μL
HERC2-IGFBP6-20-GRGO 20 (40 μL) 200 μL
HERC2-IGFBP6-20-GRGR 20 (40 μL) 200 μL
HERC2-IGFBP6-20-GRAQ 20 (40 μL) 200 μL
HERC2-IGFBP6-20-AQRE 20 (40 μL) 200 μL
HERC2-IGFBP6-20-AQOR 20 (40 μL) 200 μL
HERC2-IGFBP6-20-AQGO 20 (40 μL) 200 μL
HERC2-IGFBP6-20-AQGR 20 (40 μL) 200 μL
HERC2-IGFBP6-20-AQAQ 20 (40 μL) 200 μL

IGFBP6 Gene Summary

The Insulin Like Growth Factor Binding Protein 6 (IGFBP6) gene is located on chr12 :53491435-53496128 at 12q13.13.

Gene Name: Insulin Like Growth Factor Binding Protein 6

Chromosome: CHR12: 53491435 -53496128

Locus: 12q13.13

HERC2 Gene Summary

This gene belongs to the HERC gene family that encodes a group of unusually large proteins, which contain multiple structural domains. All members have at least 1 copy of an N-terminal region showing homology to the cell cycle regulator RCC1 and a C-terminal HECT (homologous to E6-AP C terminus) domain found in a number of E3 ubiquitin protein ligases. Genetic variations in this gene are associated with skin/hair/eye pigmentation variability. Multiple pseudogenes of this gene are located on chromosomes 15 and 16. [provided by RefSeq, Mar 2012]

Gene Name: HECT And RLD Domain Containing E3 Ubiquitin Protein Ligase 2

Chromosome: CHR15: 28356187 -28567295

Locus: 15q13.1

Gene Diseases

The HERC2 IGFBP6 Fusion has been associated with the following diseases:

Disease Name
Skin Cutaneous Melanoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.