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HIPK2-MYCBP2 Fusion FISH Probe

The HIPK2-MYCBP2 Fusion FISH Probe is used to confirm a fusion of the HIPK2 and MYCBP2 genes. The fusion of the HIPK2 and MYCBP2 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
HIPK2-MYCBP2-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
HIPK2-MYCBP2-20-RERE 20 (40 μL) 200 μL
HIPK2-MYCBP2-20-REOR 20 (40 μL) 200 μL
HIPK2-MYCBP2-20-REGO 20 (40 μL) 200 μL
HIPK2-MYCBP2-20-REGR 20 (40 μL) 200 μL
HIPK2-MYCBP2-20-REAQ 20 (40 μL) 200 μL
HIPK2-MYCBP2-20-ORRE 20 (40 μL) 200 μL
HIPK2-MYCBP2-20-OROR 20 (40 μL) 200 μL
HIPK2-MYCBP2-20-ORGO 20 (40 μL) 200 μL
HIPK2-MYCBP2-20-ORAQ 20 (40 μL) 200 μL
HIPK2-MYCBP2-20-GORE 20 (40 μL) 200 μL
HIPK2-MYCBP2-20-GOOR 20 (40 μL) 200 μL
HIPK2-MYCBP2-20-GOGO 20 (40 μL) 200 μL
HIPK2-MYCBP2-20-GOGR 20 (40 μL) 200 μL
HIPK2-MYCBP2-20-GOAQ 20 (40 μL) 200 μL
HIPK2-MYCBP2-20-GRRE 20 (40 μL) 200 μL
HIPK2-MYCBP2-20-GROR 20 (40 μL) 200 μL
HIPK2-MYCBP2-20-GRGO 20 (40 μL) 200 μL
HIPK2-MYCBP2-20-GRGR 20 (40 μL) 200 μL
HIPK2-MYCBP2-20-GRAQ 20 (40 μL) 200 μL
HIPK2-MYCBP2-20-AQRE 20 (40 μL) 200 μL
HIPK2-MYCBP2-20-AQOR 20 (40 μL) 200 μL
HIPK2-MYCBP2-20-AQGO 20 (40 μL) 200 μL
HIPK2-MYCBP2-20-AQGR 20 (40 μL) 200 μL
HIPK2-MYCBP2-20-AQAQ 20 (40 μL) 200 μL

MYCBP2 Gene Summary

This gene encodes an E3 ubiquitin-protein ligase and member of the PHR (Phr1/MYCBP2, highwire and RPM-1) family of proteins. The encoded protein plays a role in axon guidance and synapse formation in the developing nervous system. In mammalian cells, this protein regulates the cAMP and mTOR signaling pathways, and may additionally regulate autophagy. Reduced expression of this gene has been observed in acute lymphoblastic leukemia patients and a mutation in this gene has been identified in patients with a rare inherited vision defect. [provided by RefSeq, Mar 2017]

Gene Name: MYC Binding Protein 2, E3 Ubiquitin Protein Ligase

Chromosome: CHR13: 77618791 -77901177

Locus: 13q22.3

HIPK2 Gene Summary

This gene encodes a conserved serine/threonine kinase that is a member of the homeodomain-interacting protein kinase family. The encoded protein interacts with homeodomain transcription factors and many other transcription factors such as p53, and can function as both a corepressor and a coactivator depending on the transcription factor and its subcellular localization. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]

Gene Name: Homeodomain Interacting Protein Kinase 2

Chromosome: CHR7: 139246315 -139477693

Locus: 7q34

Gene Diseases

The HIPK2 MYCBP2 Fusion has been associated with the following diseases:

Disease Name
Prostate Adenocarcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.