HIST1H3D-HIST1H2BD Fusion FISH Probe
The HIST1H3D-HIST1H2BD Fusion FISH Probe is used to confirm a fusion of the HIST1H3D and HIST1H2BD genes. The fusion of the HIST1H3D and HIST1H2BD genes has been associated with Cervical Squamous Cell Carcinoma And Endocervical Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| HIST1H3D-HIST1H2BD-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| HIST1H3D-HIST1H2BD-20-RERE | 20 (40 μL) | 200 μL |
|
|
| HIST1H3D-HIST1H2BD-20-REOR | 20 (40 μL) | 200 μL |
|
|
| HIST1H3D-HIST1H2BD-20-REGO | 20 (40 μL) | 200 μL |
|
|
| HIST1H3D-HIST1H2BD-20-REGR | 20 (40 μL) | 200 μL |
|
|
| HIST1H3D-HIST1H2BD-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| HIST1H3D-HIST1H2BD-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| HIST1H3D-HIST1H2BD-20-OROR | 20 (40 μL) | 200 μL |
|
|
| HIST1H3D-HIST1H2BD-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| HIST1H3D-HIST1H2BD-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| HIST1H3D-HIST1H2BD-20-GORE | 20 (40 μL) | 200 μL |
|
|
| HIST1H3D-HIST1H2BD-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| HIST1H3D-HIST1H2BD-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| HIST1H3D-HIST1H2BD-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| HIST1H3D-HIST1H2BD-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| HIST1H3D-HIST1H2BD-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| HIST1H3D-HIST1H2BD-20-GROR | 20 (40 μL) | 200 μL |
|
|
| HIST1H3D-HIST1H2BD-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| HIST1H3D-HIST1H2BD-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| HIST1H3D-HIST1H2BD-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| HIST1H3D-HIST1H2BD-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| HIST1H3D-HIST1H2BD-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| HIST1H3D-HIST1H2BD-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| HIST1H3D-HIST1H2BD-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| HIST1H3D-HIST1H2BD-20-AQAQ | 20 (40 μL) | 200 μL |
|
HIST1H2BD Gene Summary
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2B family. Two transcripts that encode the same protein have been identified for this gene, which is found in the large histone gene cluster on chromosome 6p22-p21.3. [provided by RefSeq, Aug 2015]
Gene Name: Histone Cluster 1 H2B Family Member D
Chromosome: CHR6: 26158348 -26171576
Locus: 6p22.2
HIST1H3D Gene Summary
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6. [provided by RefSeq, Aug 2015]
Gene Name: Histone Cluster 1 H3 Family Member D
Chromosome: CHR6: 26197011 -26199464
Locus: 6p22.2
Gene Diseases
The HIST1H3D HIST1H2BD Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Cervical Squamous Cell Carcinoma And Endocervical Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|