HNRNPAB-SAMM50 Fusion FISH Probe
The HNRNPAB-SAMM50 Fusion FISH Probe is used to confirm a fusion of the HNRNPAB and SAMM50 genes. The fusion of the HNRNPAB and SAMM50 genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| HNRNPAB-SAMM50-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| HNRNPAB-SAMM50-20-RERE | 20 (40 μL) | 200 μL |
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| HNRNPAB-SAMM50-20-REOR | 20 (40 μL) | 200 μL |
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| HNRNPAB-SAMM50-20-REGO | 20 (40 μL) | 200 μL |
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| HNRNPAB-SAMM50-20-REGR | 20 (40 μL) | 200 μL |
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| HNRNPAB-SAMM50-20-REAQ | 20 (40 μL) | 200 μL |
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| HNRNPAB-SAMM50-20-ORRE | 20 (40 μL) | 200 μL |
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| HNRNPAB-SAMM50-20-OROR | 20 (40 μL) | 200 μL |
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| HNRNPAB-SAMM50-20-ORGO | 20 (40 μL) | 200 μL |
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| HNRNPAB-SAMM50-20-ORAQ | 20 (40 μL) | 200 μL |
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| HNRNPAB-SAMM50-20-GORE | 20 (40 μL) | 200 μL |
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| HNRNPAB-SAMM50-20-GOOR | 20 (40 μL) | 200 μL |
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| HNRNPAB-SAMM50-20-GOGO | 20 (40 μL) | 200 μL |
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| HNRNPAB-SAMM50-20-GOGR | 20 (40 μL) | 200 μL |
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| HNRNPAB-SAMM50-20-GOAQ | 20 (40 μL) | 200 μL |
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| HNRNPAB-SAMM50-20-GRRE | 20 (40 μL) | 200 μL |
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| HNRNPAB-SAMM50-20-GROR | 20 (40 μL) | 200 μL |
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| HNRNPAB-SAMM50-20-GRGO | 20 (40 μL) | 200 μL |
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| HNRNPAB-SAMM50-20-GRGR | 20 (40 μL) | 200 μL |
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| HNRNPAB-SAMM50-20-GRAQ | 20 (40 μL) | 200 μL |
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| HNRNPAB-SAMM50-20-AQRE | 20 (40 μL) | 200 μL |
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| HNRNPAB-SAMM50-20-AQOR | 20 (40 μL) | 200 μL |
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| HNRNPAB-SAMM50-20-AQGO | 20 (40 μL) | 200 μL |
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| HNRNPAB-SAMM50-20-AQGR | 20 (40 μL) | 200 μL |
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| HNRNPAB-SAMM50-20-AQAQ | 20 (40 μL) | 200 μL |
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HNRNPAB Gene Summary
This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are produced by RNA polymerase II and are components of the heterogeneous nuclear RNA (hnRNA) complexes. They are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene, which binds to one of the components of the multiprotein editosome complex, has two repeats of quasi-RRM (RNA recognition motif) domains that bind to RNAs. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Heterogeneous Nuclear Ribonucleoprotein A/B
Chromosome: CHR5: 177631507 -177638184
Locus: 5q35.3
SAMM50 Gene Summary
This gene encodes a component of the Sorting and Assembly Machinery (SAM) of the mitochondrial outer membrane. The Sam complex functions in the assembly of beta-barrel proteins into the outer mitochondrial membrane.[provided by RefSeq, Jun 2011]
Gene Name: SAMM50 Sorting And Assembly Machinery Component
Chromosome: CHR22: 44351260 -44392412
Locus: 22q13.31
Gene Diseases
The HNRNPAB SAMM50 Fusion has been associated with the following diseases:
| Disease Name |
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| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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