HOOK1-FGGY Fusion FISH Probe
The HOOK1-FGGY Fusion FISH Probe is used to confirm a fusion of the HOOK1 and FGGY genes. The fusion of the HOOK1 and FGGY genes has been associated with Uterine Corpus Endometrial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| HOOK1-FGGY-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| HOOK1-FGGY-20-RERE | 20 (40 μL) | 200 μL |
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| HOOK1-FGGY-20-REOR | 20 (40 μL) | 200 μL |
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| HOOK1-FGGY-20-REGO | 20 (40 μL) | 200 μL |
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| HOOK1-FGGY-20-REGR | 20 (40 μL) | 200 μL |
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| HOOK1-FGGY-20-REAQ | 20 (40 μL) | 200 μL |
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| HOOK1-FGGY-20-ORRE | 20 (40 μL) | 200 μL |
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| HOOK1-FGGY-20-OROR | 20 (40 μL) | 200 μL |
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| HOOK1-FGGY-20-ORGO | 20 (40 μL) | 200 μL |
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| HOOK1-FGGY-20-ORAQ | 20 (40 μL) | 200 μL |
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| HOOK1-FGGY-20-GORE | 20 (40 μL) | 200 μL |
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| HOOK1-FGGY-20-GOOR | 20 (40 μL) | 200 μL |
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| HOOK1-FGGY-20-GOGO | 20 (40 μL) | 200 μL |
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| HOOK1-FGGY-20-GOGR | 20 (40 μL) | 200 μL |
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| HOOK1-FGGY-20-GOAQ | 20 (40 μL) | 200 μL |
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| HOOK1-FGGY-20-GRRE | 20 (40 μL) | 200 μL |
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| HOOK1-FGGY-20-GROR | 20 (40 μL) | 200 μL |
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| HOOK1-FGGY-20-GRGO | 20 (40 μL) | 200 μL |
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| HOOK1-FGGY-20-GRGR | 20 (40 μL) | 200 μL |
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| HOOK1-FGGY-20-GRAQ | 20 (40 μL) | 200 μL |
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| HOOK1-FGGY-20-AQRE | 20 (40 μL) | 200 μL |
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| HOOK1-FGGY-20-AQOR | 20 (40 μL) | 200 μL |
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| HOOK1-FGGY-20-AQGO | 20 (40 μL) | 200 μL |
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| HOOK1-FGGY-20-AQGR | 20 (40 μL) | 200 μL |
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| HOOK1-FGGY-20-AQAQ | 20 (40 μL) | 200 μL |
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HOOK1 Gene Summary
This gene encodes a member of the hook family of coiled-coil proteins, which bind to microtubules and organelles through their N- and C-terminal domains, respectively. The encoded protein localizes to discrete punctuate subcellular structures, and interacts with several members of the Rab GTPase family involved in endocytosis. It is thought to link endocytic membrane trafficking to the microtubule cytoskeleton. Several alternatively spliced transcript variants have been identified, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jul 2008]
Gene Name: Hook Microtubule Tethering Protein 1
Chromosome: CHR1: 60280532 -60342050
Locus: 1p32.1
FGGY Gene Summary
This gene encodes a protein that phosphorylates carbohydrates such as ribulose, ribitol, and L-arabinitol. Genome-wide association studies in some populations have found an association between polymorphisms in this gene and sporadic amyotrophic lateral sclerosis, but studies of other populations have not been able to replicate this association. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013]
Gene Name: FGGY Carbohydrate Kinase Domain Containing
Chromosome: CHR1: 59762624 -60228402
Locus: 1p32.1
Gene Diseases
The HOOK1 FGGY Fusion has been associated with the following diseases:
| Disease Name |
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| Uterine Corpus Endometrial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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