HOXD3-CHN1 Fusion FISH Probe
The HOXD3-CHN1 Fusion FISH Probe is used to confirm a fusion of the HOXD3 and CHN1 genes. The fusion of the HOXD3 and CHN1 genes has been associated with Esophageal Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| HOXD3-CHN1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| HOXD3-CHN1-20-RERE | 20 (40 μL) | 200 μL |
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| HOXD3-CHN1-20-REOR | 20 (40 μL) | 200 μL |
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| HOXD3-CHN1-20-REGO | 20 (40 μL) | 200 μL |
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| HOXD3-CHN1-20-REGR | 20 (40 μL) | 200 μL |
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| HOXD3-CHN1-20-REAQ | 20 (40 μL) | 200 μL |
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| HOXD3-CHN1-20-ORRE | 20 (40 μL) | 200 μL |
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| HOXD3-CHN1-20-OROR | 20 (40 μL) | 200 μL |
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| HOXD3-CHN1-20-ORGO | 20 (40 μL) | 200 μL |
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| HOXD3-CHN1-20-ORAQ | 20 (40 μL) | 200 μL |
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| HOXD3-CHN1-20-GORE | 20 (40 μL) | 200 μL |
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| HOXD3-CHN1-20-GOOR | 20 (40 μL) | 200 μL |
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| HOXD3-CHN1-20-GOGO | 20 (40 μL) | 200 μL |
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| HOXD3-CHN1-20-GOGR | 20 (40 μL) | 200 μL |
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| HOXD3-CHN1-20-GOAQ | 20 (40 μL) | 200 μL |
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| HOXD3-CHN1-20-GRRE | 20 (40 μL) | 200 μL |
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| HOXD3-CHN1-20-GROR | 20 (40 μL) | 200 μL |
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| HOXD3-CHN1-20-GRGO | 20 (40 μL) | 200 μL |
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| HOXD3-CHN1-20-GRGR | 20 (40 μL) | 200 μL |
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| HOXD3-CHN1-20-GRAQ | 20 (40 μL) | 200 μL |
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| HOXD3-CHN1-20-AQRE | 20 (40 μL) | 200 μL |
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| HOXD3-CHN1-20-AQOR | 20 (40 μL) | 200 μL |
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| HOXD3-CHN1-20-AQGO | 20 (40 μL) | 200 μL |
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| HOXD3-CHN1-20-AQGR | 20 (40 μL) | 200 μL |
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| HOXD3-CHN1-20-AQAQ | 20 (40 μL) | 200 μL |
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CHN1 Gene Summary
This gene encodes GTPase-activating protein for ras-related p21-rac and a phorbol ester receptor. It is predominantly expressed in neurons, and plays an important role in neuronal signal-transduction mechanisms. Mutations in this gene are associated with Duane's retraction syndrome 2 (DURS2). Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Apr 2011]
Gene Name: Chimerin 1
Chromosome: CHR2: 175664041 -175870107
Locus: 2q31.1
HOXD3 Gene Summary
This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located at 2q31-2q37 chromosome regions. Deletions that removed the entire HOXD gene cluster or 5' end of this cluster have been associated with severe limb and genital abnormalities. The protein encoded by this gene may play a role in the regulation of cell adhesion processes. [provided by RefSeq, Jul 2008]
Gene Name: Homeobox D3
Chromosome: CHR2: 177028804 -177037826
Locus: 2q31.1
Gene Diseases
The HOXD3 CHN1 Fusion has been associated with the following diseases:
| Disease Name |
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| Esophageal Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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