HPS5-SETD5 Fusion FISH Probe
The HPS5-SETD5 Fusion FISH Probe is used to confirm a fusion of the HPS5 and SETD5 genes. The fusion of the HPS5 and SETD5 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| HPS5-SETD5-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| HPS5-SETD5-20-RERE | 20 (40 μL) | 200 μL |
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| HPS5-SETD5-20-REOR | 20 (40 μL) | 200 μL |
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| HPS5-SETD5-20-REGO | 20 (40 μL) | 200 μL |
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| HPS5-SETD5-20-REGR | 20 (40 μL) | 200 μL |
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| HPS5-SETD5-20-REAQ | 20 (40 μL) | 200 μL |
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| HPS5-SETD5-20-ORRE | 20 (40 μL) | 200 μL |
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| HPS5-SETD5-20-OROR | 20 (40 μL) | 200 μL |
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| HPS5-SETD5-20-ORGO | 20 (40 μL) | 200 μL |
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| HPS5-SETD5-20-ORAQ | 20 (40 μL) | 200 μL |
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| HPS5-SETD5-20-GORE | 20 (40 μL) | 200 μL |
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| HPS5-SETD5-20-GOOR | 20 (40 μL) | 200 μL |
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| HPS5-SETD5-20-GOGO | 20 (40 μL) | 200 μL |
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| HPS5-SETD5-20-GOGR | 20 (40 μL) | 200 μL |
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| HPS5-SETD5-20-GOAQ | 20 (40 μL) | 200 μL |
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| HPS5-SETD5-20-GRRE | 20 (40 μL) | 200 μL |
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| HPS5-SETD5-20-GROR | 20 (40 μL) | 200 μL |
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| HPS5-SETD5-20-GRGO | 20 (40 μL) | 200 μL |
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| HPS5-SETD5-20-GRGR | 20 (40 μL) | 200 μL |
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| HPS5-SETD5-20-GRAQ | 20 (40 μL) | 200 μL |
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| HPS5-SETD5-20-AQRE | 20 (40 μL) | 200 μL |
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| HPS5-SETD5-20-AQOR | 20 (40 μL) | 200 μL |
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| HPS5-SETD5-20-AQGO | 20 (40 μL) | 200 μL |
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| HPS5-SETD5-20-AQGR | 20 (40 μL) | 200 μL |
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| HPS5-SETD5-20-AQAQ | 20 (40 μL) | 200 μL |
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HPS5 Gene Summary
This gene encodes a protein that may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. This protein interacts with Hermansky-Pudlak syndrome 6 protein and may interact with the cytoplasmic domain of integrin, alpha-3. Mutations in this gene are associated with Hermansky-Pudlak syndrome type 5. Multiple transcript variants encoding two distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
Gene Name: HPS5, Biogenesis Of Lysosomal Organelles Complex 2 Subunit 2
Chromosome: CHR11: 18300216 -18343721
Locus: 11p15.1
SETD5 Gene Summary
This function of this gene has yet to be determined but based on sequence similarity to other SET domain proteins it may function as a histone methyltransferase. Mutations in this gene have been associated with an autosomal dominant form of intellectual disability. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2017]
Gene Name: SET Domain Containing 5
Chromosome: CHR3: 9439402 -9519838
Locus: 3p25.3
Gene Diseases
The HPS5 SETD5 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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