HSF1-ADAMTS12 Fusion FISH Probe
The HSF1-ADAMTS12 Fusion FISH Probe is used to confirm a fusion of the HSF1 and ADAMTS12 genes. The fusion of the HSF1 and ADAMTS12 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| HSF1-ADAMTS12-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| HSF1-ADAMTS12-20-RERE | 20 (40 μL) | 200 μL |
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| HSF1-ADAMTS12-20-REOR | 20 (40 μL) | 200 μL |
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| HSF1-ADAMTS12-20-REGO | 20 (40 μL) | 200 μL |
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| HSF1-ADAMTS12-20-REGR | 20 (40 μL) | 200 μL |
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| HSF1-ADAMTS12-20-REAQ | 20 (40 μL) | 200 μL |
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| HSF1-ADAMTS12-20-ORRE | 20 (40 μL) | 200 μL |
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| HSF1-ADAMTS12-20-OROR | 20 (40 μL) | 200 μL |
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| HSF1-ADAMTS12-20-ORGO | 20 (40 μL) | 200 μL |
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| HSF1-ADAMTS12-20-ORAQ | 20 (40 μL) | 200 μL |
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| HSF1-ADAMTS12-20-GORE | 20 (40 μL) | 200 μL |
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| HSF1-ADAMTS12-20-GOOR | 20 (40 μL) | 200 μL |
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| HSF1-ADAMTS12-20-GOGO | 20 (40 μL) | 200 μL |
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| HSF1-ADAMTS12-20-GOGR | 20 (40 μL) | 200 μL |
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| HSF1-ADAMTS12-20-GOAQ | 20 (40 μL) | 200 μL |
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| HSF1-ADAMTS12-20-GRRE | 20 (40 μL) | 200 μL |
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| HSF1-ADAMTS12-20-GROR | 20 (40 μL) | 200 μL |
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| HSF1-ADAMTS12-20-GRGO | 20 (40 μL) | 200 μL |
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| HSF1-ADAMTS12-20-GRGR | 20 (40 μL) | 200 μL |
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| HSF1-ADAMTS12-20-GRAQ | 20 (40 μL) | 200 μL |
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| HSF1-ADAMTS12-20-AQRE | 20 (40 μL) | 200 μL |
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| HSF1-ADAMTS12-20-AQOR | 20 (40 μL) | 200 μL |
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| HSF1-ADAMTS12-20-AQGO | 20 (40 μL) | 200 μL |
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| HSF1-ADAMTS12-20-AQGR | 20 (40 μL) | 200 μL |
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| HSF1-ADAMTS12-20-AQAQ | 20 (40 μL) | 200 μL |
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HSF1 Gene Summary
The product of this gene is a transcription factor that is rapidly induced after temperature stress and binds heat shock promoter elements (HSE). This protein plays a role in the regulation of lifespan. Expression of this gene is repressed by phosphorylation, which promotes binding by heat shock protein 90. [provided by RefSeq, Jul 2017]
Gene Name: Heat Shock Transcription Factor 1
Chromosome: CHR8: 145515269 -145538385
Locus: 8q24.3
ADAMTS12 Gene Summary
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS-1) motif. Individual members of this family differ in the number of C-terminal TS-1 motifs, and some have unique C-terminal domains. The enzyme encoded by this gene contains eight TS-1 motifs. It may play roles in pulmonary cells during fetal development or in tumor processes through its proteolytic activity or as a molecule potentially involved in regulation of cell adhesion. [provided by RefSeq, Jul 2008]
Gene Name: ADAM Metallopeptidase With Thrombospondin Type 1 Motif 12
Chromosome: CHR5: 33527286 -33892124
Locus: 5p13.3-p13.2
Gene Diseases
The HSF1 ADAMTS12 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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