ICAM1-HNRNPM Fusion FISH Probe
The ICAM1-HNRNPM Fusion FISH Probe is used to confirm a fusion of the ICAM1 and HNRNPM genes. The fusion of the ICAM1 and HNRNPM genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ICAM1-HNRNPM-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ICAM1-HNRNPM-20-RERE | 20 (40 μL) | 200 μL |
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| ICAM1-HNRNPM-20-REOR | 20 (40 μL) | 200 μL |
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| ICAM1-HNRNPM-20-REGO | 20 (40 μL) | 200 μL |
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| ICAM1-HNRNPM-20-REGR | 20 (40 μL) | 200 μL |
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| ICAM1-HNRNPM-20-REAQ | 20 (40 μL) | 200 μL |
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| ICAM1-HNRNPM-20-ORRE | 20 (40 μL) | 200 μL |
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| ICAM1-HNRNPM-20-OROR | 20 (40 μL) | 200 μL |
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| ICAM1-HNRNPM-20-ORGO | 20 (40 μL) | 200 μL |
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| ICAM1-HNRNPM-20-ORAQ | 20 (40 μL) | 200 μL |
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| ICAM1-HNRNPM-20-GORE | 20 (40 μL) | 200 μL |
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| ICAM1-HNRNPM-20-GOOR | 20 (40 μL) | 200 μL |
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| ICAM1-HNRNPM-20-GOGO | 20 (40 μL) | 200 μL |
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| ICAM1-HNRNPM-20-GOGR | 20 (40 μL) | 200 μL |
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| ICAM1-HNRNPM-20-GOAQ | 20 (40 μL) | 200 μL |
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| ICAM1-HNRNPM-20-GRRE | 20 (40 μL) | 200 μL |
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| ICAM1-HNRNPM-20-GROR | 20 (40 μL) | 200 μL |
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| ICAM1-HNRNPM-20-GRGO | 20 (40 μL) | 200 μL |
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| ICAM1-HNRNPM-20-GRGR | 20 (40 μL) | 200 μL |
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| ICAM1-HNRNPM-20-GRAQ | 20 (40 μL) | 200 μL |
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| ICAM1-HNRNPM-20-AQRE | 20 (40 μL) | 200 μL |
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| ICAM1-HNRNPM-20-AQOR | 20 (40 μL) | 200 μL |
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| ICAM1-HNRNPM-20-AQGO | 20 (40 μL) | 200 μL |
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| ICAM1-HNRNPM-20-AQGR | 20 (40 μL) | 200 μL |
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| ICAM1-HNRNPM-20-AQAQ | 20 (40 μL) | 200 μL |
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ICAM1 Gene Summary
This gene encodes a cell surface glycoprotein which is typically expressed on endothelial cells and cells of the immune system. It binds to integrins of type CD11a / CD18, or CD11b / CD18 and is also exploited by Rhinovirus as a receptor. [provided by RefSeq, Jul 2008]
Gene Name: Intercellular Adhesion Molecule 1
Chromosome: CHR19: 10381516 -10397291
Locus: 19p13.2
HNRNPM Gene Summary
This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that bind to RNAs. This protein also constitutes a monomer of the N-acetylglucosamine-specific receptor which is postulated to trigger selective recycling of immature GlcNAc-bearing thyroglobulin molecules. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2011]
Gene Name: Heterogeneous Nuclear Ribonucleoprotein M
Chromosome: CHR19: 8509802 -8554002
Locus: 19p13.2
Gene Diseases
The ICAM1 HNRNPM Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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