ICOSLG-KCNJ6 Fusion FISH Probe
The ICOSLG-KCNJ6 Fusion FISH Probe is used to confirm a fusion of the ICOSLG and KCNJ6 genes. The fusion of the ICOSLG and KCNJ6 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ICOSLG-KCNJ6-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ICOSLG-KCNJ6-20-RERE | 20 (40 μL) | 200 μL |
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| ICOSLG-KCNJ6-20-REOR | 20 (40 μL) | 200 μL |
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| ICOSLG-KCNJ6-20-REGO | 20 (40 μL) | 200 μL |
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| ICOSLG-KCNJ6-20-REGR | 20 (40 μL) | 200 μL |
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| ICOSLG-KCNJ6-20-REAQ | 20 (40 μL) | 200 μL |
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| ICOSLG-KCNJ6-20-ORRE | 20 (40 μL) | 200 μL |
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| ICOSLG-KCNJ6-20-OROR | 20 (40 μL) | 200 μL |
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| ICOSLG-KCNJ6-20-ORGO | 20 (40 μL) | 200 μL |
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| ICOSLG-KCNJ6-20-ORAQ | 20 (40 μL) | 200 μL |
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| ICOSLG-KCNJ6-20-GORE | 20 (40 μL) | 200 μL |
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| ICOSLG-KCNJ6-20-GOOR | 20 (40 μL) | 200 μL |
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| ICOSLG-KCNJ6-20-GOGO | 20 (40 μL) | 200 μL |
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| ICOSLG-KCNJ6-20-GOGR | 20 (40 μL) | 200 μL |
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| ICOSLG-KCNJ6-20-GOAQ | 20 (40 μL) | 200 μL |
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| ICOSLG-KCNJ6-20-GRRE | 20 (40 μL) | 200 μL |
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| ICOSLG-KCNJ6-20-GROR | 20 (40 μL) | 200 μL |
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| ICOSLG-KCNJ6-20-GRGO | 20 (40 μL) | 200 μL |
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| ICOSLG-KCNJ6-20-GRGR | 20 (40 μL) | 200 μL |
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| ICOSLG-KCNJ6-20-GRAQ | 20 (40 μL) | 200 μL |
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| ICOSLG-KCNJ6-20-AQRE | 20 (40 μL) | 200 μL |
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| ICOSLG-KCNJ6-20-AQOR | 20 (40 μL) | 200 μL |
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| ICOSLG-KCNJ6-20-AQGO | 20 (40 μL) | 200 μL |
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| ICOSLG-KCNJ6-20-AQGR | 20 (40 μL) | 200 μL |
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| ICOSLG-KCNJ6-20-AQAQ | 20 (40 μL) | 200 μL |
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KCNJ6 Gene Summary
This gene encodes a member of the G protein-coupled inwardly-rectifying potassium channel family of inward rectifier potassium channels. This type of potassium channel allows a greater flow of potassium into the cell than out of it. These proteins modulate many physiological processes, including heart rate in cardiac cells and circuit activity in neuronal cells, through G-protein coupled receptor stimulation. Mutations in this gene are associated with Keppen-Lubinsky Syndrome, a rare condition characterized by severe developmental delay, facial dysmorphism, and intellectual disability. [provided by RefSeq, Apr 2015]
Gene Name: Potassium Voltage-gated Channel Subfamily J Member 6
Chromosome: CHR21: 38996785 -39288696
Locus: 21q22.13
ICOSLG Gene Summary
The Inducible T-cell Costimulator Ligand (ICOSLG) gene is located on chr21 :45646721-45660834 at 21q22.3.
Gene Name: Inducible T-cell Costimulator Ligand
Chromosome: CHR21: 45646721 -45660834
Locus: 21q22.3
Gene Diseases
The ICOSLG KCNJ6 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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