IDE-CAMK1D Fusion FISH Probe
The IDE-CAMK1D Fusion FISH Probe is used to confirm a fusion of the IDE and CAMK1D genes. The fusion of the IDE and CAMK1D genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| IDE-CAMK1D-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| IDE-CAMK1D-20-RERE | 20 (40 μL) | 200 μL |
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| IDE-CAMK1D-20-REOR | 20 (40 μL) | 200 μL |
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| IDE-CAMK1D-20-REGO | 20 (40 μL) | 200 μL |
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| IDE-CAMK1D-20-REGR | 20 (40 μL) | 200 μL |
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| IDE-CAMK1D-20-REAQ | 20 (40 μL) | 200 μL |
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| IDE-CAMK1D-20-ORRE | 20 (40 μL) | 200 μL |
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| IDE-CAMK1D-20-OROR | 20 (40 μL) | 200 μL |
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| IDE-CAMK1D-20-ORGO | 20 (40 μL) | 200 μL |
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| IDE-CAMK1D-20-ORAQ | 20 (40 μL) | 200 μL |
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| IDE-CAMK1D-20-GORE | 20 (40 μL) | 200 μL |
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| IDE-CAMK1D-20-GOOR | 20 (40 μL) | 200 μL |
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| IDE-CAMK1D-20-GOGO | 20 (40 μL) | 200 μL |
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| IDE-CAMK1D-20-GOGR | 20 (40 μL) | 200 μL |
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| IDE-CAMK1D-20-GOAQ | 20 (40 μL) | 200 μL |
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| IDE-CAMK1D-20-GRRE | 20 (40 μL) | 200 μL |
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| IDE-CAMK1D-20-GROR | 20 (40 μL) | 200 μL |
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| IDE-CAMK1D-20-GRGO | 20 (40 μL) | 200 μL |
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| IDE-CAMK1D-20-GRGR | 20 (40 μL) | 200 μL |
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| IDE-CAMK1D-20-GRAQ | 20 (40 μL) | 200 μL |
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| IDE-CAMK1D-20-AQRE | 20 (40 μL) | 200 μL |
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| IDE-CAMK1D-20-AQOR | 20 (40 μL) | 200 μL |
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| IDE-CAMK1D-20-AQGO | 20 (40 μL) | 200 μL |
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| IDE-CAMK1D-20-AQGR | 20 (40 μL) | 200 μL |
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| IDE-CAMK1D-20-AQAQ | 20 (40 μL) | 200 μL |
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IDE Gene Summary
This gene encodes a zinc metallopeptidase that degrades intracellular insulin, and thereby terminates insulins activity, as well as participating in intercellular peptide signalling by degrading diverse peptides such as glucagon, amylin, bradykinin, and kallidin. The preferential affinity of this enzyme for insulin results in insulin-mediated inhibition of the degradation of other peptides such as beta-amyloid. Deficiencies in this protein's function are associated with Alzheimer's disease and type 2 diabetes mellitus but mutations in this gene have not been shown to be causitive for these diseases. This protein localizes primarily to the cytoplasm but in some cell types localizes to the extracellular space, cell membrane, peroxisome, and mitochondrion. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described but have not been experimentally verified.[provided by RefSeq, Sep 2009]
Gene Name: Insulin Degrading Enzyme
Chromosome: CHR10: 94211440 -94333852
Locus: 10q23.33
CAMK1D Gene Summary
This gene is a member of the calcium/calmodulin-dependent protein kinase 1 family, a subfamily of the serine/threonine kinases. The encoded protein is a component of the calcium-regulated calmodulin-dependent protein kinase cascade. It has been associated with multiple processes including regulation of granulocyte function, activation of CREB-dependent gene transcription, aldosterone synthesis, differentiation and activation of neutrophil cells, and apoptosis of erythroleukemia cells. Alternatively spliced transcript variants encoding different isoforms of this gene have been described. [provided by RefSeq, Jan 2015]
Gene Name: Calcium/calmodulin Dependent Protein Kinase ID
Chromosome: CHR10: 12391582 -12871733
Locus: 10p13
Gene Diseases
The IDE CAMK1D Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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