IFNGR2-NUDCD3 Fusion FISH Probe
The IFNGR2-NUDCD3 Fusion FISH Probe is used to confirm a fusion of the IFNGR2 and NUDCD3 genes. The fusion of the IFNGR2 and NUDCD3 genes has been associated with Pancreatic Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| IFNGR2-NUDCD3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| IFNGR2-NUDCD3-20-RERE | 20 (40 μL) | 200 μL |
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| IFNGR2-NUDCD3-20-REOR | 20 (40 μL) | 200 μL |
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| IFNGR2-NUDCD3-20-REGO | 20 (40 μL) | 200 μL |
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| IFNGR2-NUDCD3-20-REGR | 20 (40 μL) | 200 μL |
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| IFNGR2-NUDCD3-20-REAQ | 20 (40 μL) | 200 μL |
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| IFNGR2-NUDCD3-20-ORRE | 20 (40 μL) | 200 μL |
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| IFNGR2-NUDCD3-20-OROR | 20 (40 μL) | 200 μL |
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| IFNGR2-NUDCD3-20-ORGO | 20 (40 μL) | 200 μL |
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| IFNGR2-NUDCD3-20-ORAQ | 20 (40 μL) | 200 μL |
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| IFNGR2-NUDCD3-20-GORE | 20 (40 μL) | 200 μL |
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| IFNGR2-NUDCD3-20-GOOR | 20 (40 μL) | 200 μL |
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| IFNGR2-NUDCD3-20-GOGO | 20 (40 μL) | 200 μL |
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| IFNGR2-NUDCD3-20-GOGR | 20 (40 μL) | 200 μL |
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| IFNGR2-NUDCD3-20-GOAQ | 20 (40 μL) | 200 μL |
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| IFNGR2-NUDCD3-20-GRRE | 20 (40 μL) | 200 μL |
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| IFNGR2-NUDCD3-20-GROR | 20 (40 μL) | 200 μL |
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| IFNGR2-NUDCD3-20-GRGO | 20 (40 μL) | 200 μL |
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| IFNGR2-NUDCD3-20-GRGR | 20 (40 μL) | 200 μL |
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| IFNGR2-NUDCD3-20-GRAQ | 20 (40 μL) | 200 μL |
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| IFNGR2-NUDCD3-20-AQRE | 20 (40 μL) | 200 μL |
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| IFNGR2-NUDCD3-20-AQOR | 20 (40 μL) | 200 μL |
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| IFNGR2-NUDCD3-20-AQGO | 20 (40 μL) | 200 μL |
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| IFNGR2-NUDCD3-20-AQGR | 20 (40 μL) | 200 μL |
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| IFNGR2-NUDCD3-20-AQAQ | 20 (40 μL) | 200 μL |
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IFNGR2 Gene Summary
This gene (IFNGR2) encodes the non-ligand-binding beta chain of the gamma interferon receptor. Human interferon-gamma receptor is a heterodimer of IFNGR1 and IFNGR2. Defects in IFNGR2 are a cause of mendelian susceptibility to mycobacterial disease (MSMD), also known as familial disseminated atypical mycobacterial infection. MSMD is a genetically heterogeneous disease with autosomal recessive, autosomal dominant or X-linked inheritance. [provided by RefSeq, Jul 2008]
Gene Name: Interferon Gamma Receptor 2
Chromosome: CHR21: 34775201 -34809828
Locus: 21q22.11
NUDCD3 Gene Summary
The product of this gene functions to maintain the stability of dynein intermediate chain. Depletion of this gene product results in aggregation and degradation of dynein intermediate chain, mislocalization of the dynein complex from kinetochores, spindle microtubules, and spindle poles, and loss of gamma-tubulin from spindle poles. The protein localizes to the Golgi apparatus during interphase, and levels of the protein increase after the G1/S transition. [provided by RefSeq, Jul 2008]
Gene Name: NudC Domain Containing 3
Chromosome: CHR7: 44421964 -44530385
Locus: 7p13
Gene Diseases
The IFNGR2 NUDCD3 Fusion has been associated with the following diseases:
| Disease Name |
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| Pancreatic Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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