IGSF3-PARL Fusion FISH Probe
The IGSF3-PARL Fusion FISH Probe is used to confirm a fusion of the IGSF3 and PARL genes. The fusion of the IGSF3 and PARL genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| IGSF3-PARL-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| IGSF3-PARL-20-RERE | 20 (40 μL) | 200 μL |
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| IGSF3-PARL-20-REOR | 20 (40 μL) | 200 μL |
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| IGSF3-PARL-20-REGO | 20 (40 μL) | 200 μL |
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| IGSF3-PARL-20-REGR | 20 (40 μL) | 200 μL |
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| IGSF3-PARL-20-REAQ | 20 (40 μL) | 200 μL |
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| IGSF3-PARL-20-ORRE | 20 (40 μL) | 200 μL |
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| IGSF3-PARL-20-OROR | 20 (40 μL) | 200 μL |
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| IGSF3-PARL-20-ORGO | 20 (40 μL) | 200 μL |
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| IGSF3-PARL-20-ORAQ | 20 (40 μL) | 200 μL |
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| IGSF3-PARL-20-GORE | 20 (40 μL) | 200 μL |
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| IGSF3-PARL-20-GOOR | 20 (40 μL) | 200 μL |
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| IGSF3-PARL-20-GOGO | 20 (40 μL) | 200 μL |
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| IGSF3-PARL-20-GOGR | 20 (40 μL) | 200 μL |
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| IGSF3-PARL-20-GOAQ | 20 (40 μL) | 200 μL |
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| IGSF3-PARL-20-GRRE | 20 (40 μL) | 200 μL |
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| IGSF3-PARL-20-GROR | 20 (40 μL) | 200 μL |
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| IGSF3-PARL-20-GRGO | 20 (40 μL) | 200 μL |
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| IGSF3-PARL-20-GRGR | 20 (40 μL) | 200 μL |
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| IGSF3-PARL-20-GRAQ | 20 (40 μL) | 200 μL |
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| IGSF3-PARL-20-AQRE | 20 (40 μL) | 200 μL |
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| IGSF3-PARL-20-AQOR | 20 (40 μL) | 200 μL |
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| IGSF3-PARL-20-AQGO | 20 (40 μL) | 200 μL |
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| IGSF3-PARL-20-AQGR | 20 (40 μL) | 200 μL |
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| IGSF3-PARL-20-AQAQ | 20 (40 μL) | 200 μL |
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IGSF3 Gene Summary
The protein encoded by this gene is an immunoglobulin-like membrane protein containing several V-type Ig-like domains. A mutation in this gene has been associated with bilateral nasolacrimal duct obstruction (LCDD). [provided by RefSeq, Jun 2016]
Gene Name: Immunoglobulin Superfamily Member 3
Chromosome: CHR1: 117117030 -117210314
Locus: 1p13.1
PARL Gene Summary
This gene encodes a member of the rhomboid family of intramembrane serine proteases that is localized to the inner mitochondrial membrane. The encoded protein regulates mitochondrial remodeling and apoptosis through regulated substrate proteolysis. Proteolytic processing of the encoded protein results in the release of a small peptide, P-beta, which may transit to the nucleus. Mutations in this gene may be associated with Parkinson's disease. [provided by RefSeq, May 2016]
Gene Name: Presenilin Associated Rhomboid Like
Chromosome: CHR3: 183547172 -183602693
Locus: 3q27.1
Gene Diseases
The IGSF3 PARL Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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