IL20RB-NCK1 Fusion FISH Probe
The IL20RB-NCK1 Fusion FISH Probe is used to confirm a fusion of the IL20RB and NCK1 genes. The fusion of the IL20RB and NCK1 genes has been associated with Head And Neck Squamous Cell Carcinoma . These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| IL20RB-NCK1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| IL20RB-NCK1-20-RERE | 20 (40 μL) | 200 μL |
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| IL20RB-NCK1-20-REOR | 20 (40 μL) | 200 μL |
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| IL20RB-NCK1-20-REGO | 20 (40 μL) | 200 μL |
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| IL20RB-NCK1-20-REGR | 20 (40 μL) | 200 μL |
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| IL20RB-NCK1-20-REAQ | 20 (40 μL) | 200 μL |
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| IL20RB-NCK1-20-ORRE | 20 (40 μL) | 200 μL |
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| IL20RB-NCK1-20-OROR | 20 (40 μL) | 200 μL |
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| IL20RB-NCK1-20-ORGO | 20 (40 μL) | 200 μL |
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| IL20RB-NCK1-20-ORAQ | 20 (40 μL) | 200 μL |
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| IL20RB-NCK1-20-GORE | 20 (40 μL) | 200 μL |
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| IL20RB-NCK1-20-GOOR | 20 (40 μL) | 200 μL |
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| IL20RB-NCK1-20-GOGO | 20 (40 μL) | 200 μL |
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| IL20RB-NCK1-20-GOGR | 20 (40 μL) | 200 μL |
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| IL20RB-NCK1-20-GOAQ | 20 (40 μL) | 200 μL |
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| IL20RB-NCK1-20-GRRE | 20 (40 μL) | 200 μL |
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| IL20RB-NCK1-20-GROR | 20 (40 μL) | 200 μL |
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| IL20RB-NCK1-20-GRGO | 20 (40 μL) | 200 μL |
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| IL20RB-NCK1-20-GRGR | 20 (40 μL) | 200 μL |
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| IL20RB-NCK1-20-GRAQ | 20 (40 μL) | 200 μL |
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| IL20RB-NCK1-20-AQRE | 20 (40 μL) | 200 μL |
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| IL20RB-NCK1-20-AQOR | 20 (40 μL) | 200 μL |
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| IL20RB-NCK1-20-AQGO | 20 (40 μL) | 200 μL |
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| IL20RB-NCK1-20-AQGR | 20 (40 μL) | 200 μL |
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| IL20RB-NCK1-20-AQAQ | 20 (40 μL) | 200 μL |
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NCK1 Gene Summary
The protein encoded by this gene is one of the signaling and transforming proteins containing Src homology 2 and 3 (SH2 and SH3) domains. It is located in the cytoplasm and is an adaptor protein involved in transducing signals from receptor tyrosine kinases to downstream signal recipients such as RAS. Alternatively spliced transcript variants encoding different isoforms have been found. [provided by RefSeq, Jun 2010]
Gene Name: NCK Adaptor Protein 1
Chromosome: CHR3: 136581049 -136667968
Locus: 3q22.3
IL20RB Gene Summary
IL20RB and IL20RA (MIM 605620) form a heterodimeric receptor for interleukin-20 (IL20; MIM 605619) (Blumberg et al., 2001 [PubMed 11163236]).[supplied by OMIM, Feb 2009]
Gene Name: Interleukin 20 Receptor Subunit Beta
Chromosome: CHR3: 136676706 -136729926
Locus: 3q22.3
Gene Diseases
The IL20RB NCK1 Fusion has been associated with the following diseases:
| Disease Name |
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| Head And Neck Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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