IL34-ARG2 Fusion FISH Probe
The IL34-ARG2 Fusion FISH Probe is used to confirm a fusion of the IL34 and ARG2 genes. The fusion of the IL34 and ARG2 genes has been associated with Kidney Renal Clear Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| IL34-ARG2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| IL34-ARG2-20-RERE | 20 (40 μL) | 200 μL |
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| IL34-ARG2-20-REOR | 20 (40 μL) | 200 μL |
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| IL34-ARG2-20-REGO | 20 (40 μL) | 200 μL |
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| IL34-ARG2-20-REGR | 20 (40 μL) | 200 μL |
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| IL34-ARG2-20-REAQ | 20 (40 μL) | 200 μL |
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| IL34-ARG2-20-ORRE | 20 (40 μL) | 200 μL |
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| IL34-ARG2-20-OROR | 20 (40 μL) | 200 μL |
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| IL34-ARG2-20-ORGO | 20 (40 μL) | 200 μL |
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| IL34-ARG2-20-ORAQ | 20 (40 μL) | 200 μL |
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| IL34-ARG2-20-GORE | 20 (40 μL) | 200 μL |
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| IL34-ARG2-20-GOOR | 20 (40 μL) | 200 μL |
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| IL34-ARG2-20-GOGO | 20 (40 μL) | 200 μL |
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| IL34-ARG2-20-GOGR | 20 (40 μL) | 200 μL |
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| IL34-ARG2-20-GOAQ | 20 (40 μL) | 200 μL |
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| IL34-ARG2-20-GRRE | 20 (40 μL) | 200 μL |
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| IL34-ARG2-20-GROR | 20 (40 μL) | 200 μL |
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| IL34-ARG2-20-GRGO | 20 (40 μL) | 200 μL |
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| IL34-ARG2-20-GRGR | 20 (40 μL) | 200 μL |
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| IL34-ARG2-20-GRAQ | 20 (40 μL) | 200 μL |
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| IL34-ARG2-20-AQRE | 20 (40 μL) | 200 μL |
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| IL34-ARG2-20-AQOR | 20 (40 μL) | 200 μL |
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| IL34-ARG2-20-AQGO | 20 (40 μL) | 200 μL |
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| IL34-ARG2-20-AQGR | 20 (40 μL) | 200 μL |
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| IL34-ARG2-20-AQAQ | 20 (40 μL) | 200 μL |
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ARG2 Gene Summary
Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exists (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type II isoform encoded by this gene, is located in the mitochondria and expressed in extra-hepatic tissues, especially kidney. The physiologic role of this isoform is poorly understood; it is thought to play a role in nitric oxide and polyamine metabolism. Transcript variants of the type II gene resulting from the use of alternative polyadenylation sites have been described. [provided by RefSeq, Jul 2008]
Gene Name: Arginase 2
Chromosome: CHR14: 68086578 -68118436
Locus: 14q24.1
IL34 Gene Summary
Interleukin-34 is a cytokine that promotes the differentiation and viability of monocytes and macrophages through the colony-stimulating factor-1 receptor (CSF1R; MIM 164770) (Lin et al., 2008 [PubMed 18467591]).[supplied by OMIM, May 2008]
Gene Name: Interleukin 34
Chromosome: CHR16: 70613797 -70694585
Locus: 16q22.1
Gene Diseases
The IL34 ARG2 Fusion has been associated with the following diseases:
| Disease Name |
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| Kidney Renal Clear Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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