IL34-CNGB1 Fusion FISH Probe
The IL34-CNGB1 Fusion FISH Probe is used to confirm a fusion of the IL34 and CNGB1 genes. The fusion of the IL34 and CNGB1 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| IL34-CNGB1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| IL34-CNGB1-20-RERE | 20 (40 μL) | 200 μL |
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| IL34-CNGB1-20-REOR | 20 (40 μL) | 200 μL |
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| IL34-CNGB1-20-REGO | 20 (40 μL) | 200 μL |
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| IL34-CNGB1-20-REGR | 20 (40 μL) | 200 μL |
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| IL34-CNGB1-20-REAQ | 20 (40 μL) | 200 μL |
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| IL34-CNGB1-20-ORRE | 20 (40 μL) | 200 μL |
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| IL34-CNGB1-20-OROR | 20 (40 μL) | 200 μL |
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| IL34-CNGB1-20-ORGO | 20 (40 μL) | 200 μL |
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| IL34-CNGB1-20-ORAQ | 20 (40 μL) | 200 μL |
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| IL34-CNGB1-20-GORE | 20 (40 μL) | 200 μL |
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| IL34-CNGB1-20-GOOR | 20 (40 μL) | 200 μL |
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| IL34-CNGB1-20-GOGO | 20 (40 μL) | 200 μL |
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| IL34-CNGB1-20-GOGR | 20 (40 μL) | 200 μL |
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| IL34-CNGB1-20-GOAQ | 20 (40 μL) | 200 μL |
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| IL34-CNGB1-20-GRRE | 20 (40 μL) | 200 μL |
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| IL34-CNGB1-20-GROR | 20 (40 μL) | 200 μL |
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| IL34-CNGB1-20-GRGO | 20 (40 μL) | 200 μL |
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| IL34-CNGB1-20-GRGR | 20 (40 μL) | 200 μL |
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| IL34-CNGB1-20-GRAQ | 20 (40 μL) | 200 μL |
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| IL34-CNGB1-20-AQRE | 20 (40 μL) | 200 μL |
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| IL34-CNGB1-20-AQOR | 20 (40 μL) | 200 μL |
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| IL34-CNGB1-20-AQGO | 20 (40 μL) | 200 μL |
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| IL34-CNGB1-20-AQGR | 20 (40 μL) | 200 μL |
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| IL34-CNGB1-20-AQAQ | 20 (40 μL) | 200 μL |
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CNGB1 Gene Summary
In humans, the rod photoreceptor cGMP-gated cation channel helps regulate ion flow into the rod photoreceptor outer segment in response to light-induced alteration of the levels of intracellular cGMP. This channel consists of two subunits, alpha and beta, with the protein encoded by this gene representing the beta subunit. Defects in this gene are a cause of cause of retinitis pigmentosa type 45. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2013]
Gene Name: Cyclic Nucleotide Gated Channel Beta 1
Chromosome: CHR16: 57916243 -58005020
Locus: 16q21
IL34 Gene Summary
Interleukin-34 is a cytokine that promotes the differentiation and viability of monocytes and macrophages through the colony-stimulating factor-1 receptor (CSF1R; MIM 164770) (Lin et al., 2008 [PubMed 18467591]).[supplied by OMIM, May 2008]
Gene Name: Interleukin 34
Chromosome: CHR16: 70613797 -70694585
Locus: 16q22.1
Gene Diseases
The IL34 CNGB1 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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