IL4I1-DYRK1B Fusion FISH Probe
The IL4I1-DYRK1B Fusion FISH Probe is used to confirm a fusion of the IL4I1 and DYRK1B genes. The fusion of the IL4I1 and DYRK1B genes has been associated with Esophageal Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| IL4I1-DYRK1B-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| IL4I1-DYRK1B-20-RERE | 20 (40 μL) | 200 μL |
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| IL4I1-DYRK1B-20-REOR | 20 (40 μL) | 200 μL |
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| IL4I1-DYRK1B-20-REGO | 20 (40 μL) | 200 μL |
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| IL4I1-DYRK1B-20-REGR | 20 (40 μL) | 200 μL |
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| IL4I1-DYRK1B-20-REAQ | 20 (40 μL) | 200 μL |
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| IL4I1-DYRK1B-20-ORRE | 20 (40 μL) | 200 μL |
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| IL4I1-DYRK1B-20-OROR | 20 (40 μL) | 200 μL |
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| IL4I1-DYRK1B-20-ORGO | 20 (40 μL) | 200 μL |
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| IL4I1-DYRK1B-20-ORAQ | 20 (40 μL) | 200 μL |
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| IL4I1-DYRK1B-20-GORE | 20 (40 μL) | 200 μL |
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| IL4I1-DYRK1B-20-GOOR | 20 (40 μL) | 200 μL |
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| IL4I1-DYRK1B-20-GOGO | 20 (40 μL) | 200 μL |
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| IL4I1-DYRK1B-20-GOGR | 20 (40 μL) | 200 μL |
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| IL4I1-DYRK1B-20-GOAQ | 20 (40 μL) | 200 μL |
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| IL4I1-DYRK1B-20-GRRE | 20 (40 μL) | 200 μL |
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| IL4I1-DYRK1B-20-GROR | 20 (40 μL) | 200 μL |
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| IL4I1-DYRK1B-20-GRGO | 20 (40 μL) | 200 μL |
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| IL4I1-DYRK1B-20-GRGR | 20 (40 μL) | 200 μL |
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| IL4I1-DYRK1B-20-GRAQ | 20 (40 μL) | 200 μL |
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| IL4I1-DYRK1B-20-AQRE | 20 (40 μL) | 200 μL |
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| IL4I1-DYRK1B-20-AQOR | 20 (40 μL) | 200 μL |
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| IL4I1-DYRK1B-20-AQGO | 20 (40 μL) | 200 μL |
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| IL4I1-DYRK1B-20-AQGR | 20 (40 μL) | 200 μL |
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| IL4I1-DYRK1B-20-AQAQ | 20 (40 μL) | 200 μL |
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DYRK1B Gene Summary
This gene encodes a member of a family of nuclear-localized protein kinases. The encoded protein participates in the regulation of the cell cycle. Expression of this gene may be altered in tumor cells, and mutations in this gene were found to cause abdominal obesity-metabolic syndrome 3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014]
Gene Name: Dual Specificity Tyrosine Phosphorylation Regulated Kinase 1B
Chromosome: CHR19: 40315989 -40324841
Locus: 19q13.2
IL4I1 Gene Summary
This gene encodes a protein with limited similarity to L-amino acid oxidase which contains the conserved amino acids thought to be involved in catalysis and binding of flavin adenine dinucleotide (FAD) cofactor. The expression of this gene can be induced by interleukin 4 in B cells, however, expression of transcripts containing the first two exons of the upstream gene is found in other cell types. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]
Gene Name: Interleukin 4 Induced 1
Chromosome: CHR19: 50392913 -50432762
Locus: 19q13.33
Gene Diseases
The IL4I1 DYRK1B Fusion has been associated with the following diseases:
| Disease Name |
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| Esophageal Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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