INPP5A-CSTA Fusion FISH Probe
The INPP5A-CSTA Fusion FISH Probe is used to confirm a fusion of the INPP5A and CSTA genes. The fusion of the INPP5A and CSTA genes has been associated with Kidney Renal Clear Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| INPP5A-CSTA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| INPP5A-CSTA-20-RERE | 20 (40 μL) | 200 μL |
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| INPP5A-CSTA-20-REOR | 20 (40 μL) | 200 μL |
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| INPP5A-CSTA-20-REGO | 20 (40 μL) | 200 μL |
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| INPP5A-CSTA-20-REGR | 20 (40 μL) | 200 μL |
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| INPP5A-CSTA-20-REAQ | 20 (40 μL) | 200 μL |
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| INPP5A-CSTA-20-ORRE | 20 (40 μL) | 200 μL |
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| INPP5A-CSTA-20-OROR | 20 (40 μL) | 200 μL |
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| INPP5A-CSTA-20-ORGO | 20 (40 μL) | 200 μL |
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| INPP5A-CSTA-20-ORAQ | 20 (40 μL) | 200 μL |
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| INPP5A-CSTA-20-GORE | 20 (40 μL) | 200 μL |
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| INPP5A-CSTA-20-GOOR | 20 (40 μL) | 200 μL |
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| INPP5A-CSTA-20-GOGO | 20 (40 μL) | 200 μL |
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| INPP5A-CSTA-20-GOGR | 20 (40 μL) | 200 μL |
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| INPP5A-CSTA-20-GOAQ | 20 (40 μL) | 200 μL |
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| INPP5A-CSTA-20-GRRE | 20 (40 μL) | 200 μL |
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| INPP5A-CSTA-20-GROR | 20 (40 μL) | 200 μL |
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| INPP5A-CSTA-20-GRGO | 20 (40 μL) | 200 μL |
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| INPP5A-CSTA-20-GRGR | 20 (40 μL) | 200 μL |
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| INPP5A-CSTA-20-GRAQ | 20 (40 μL) | 200 μL |
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| INPP5A-CSTA-20-AQRE | 20 (40 μL) | 200 μL |
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| INPP5A-CSTA-20-AQOR | 20 (40 μL) | 200 μL |
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| INPP5A-CSTA-20-AQGO | 20 (40 μL) | 200 μL |
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| INPP5A-CSTA-20-AQGR | 20 (40 μL) | 200 μL |
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| INPP5A-CSTA-20-AQAQ | 20 (40 μL) | 200 μL |
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CSTA Gene Summary
The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins, and kininogens. This gene encodes a stefin that functions as a cysteine protease inhibitor, forming tight complexes with papain and the cathepsins B, H, and L. The protein is one of the precursor proteins of cornified cell envelope in keratinocytes and plays a role in epidermal development and maintenance. Stefins have been proposed as prognostic and diagnostic tools for cancer. [provided by RefSeq, Jul 2008]
Gene Name: Cystatin A
Chromosome: CHR3: 122044010 -122060815
Locus: 3q21.1
INPP5A Gene Summary
The protein encoded by this gene is a membrane-associated type I inositol 1,4,5-trisphosphate (InsP3) 5-phosphatase. InsP3 5-phosphatases hydrolyze Ins(1,4,5)P3, which mobilizes intracellular calcium and acts as a second messenger mediating cell responses to various stimulation. [provided by RefSeq, Jul 2008]
Gene Name: Inositol Polyphosphate-5-phosphatase A
Chromosome: CHR10: 134351352 -134596984
Locus: 10q26.3
Gene Diseases
The INPP5A CSTA Fusion has been associated with the following diseases:
| Disease Name |
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| Kidney Renal Clear Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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