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INSR-S1PR2 Fusion FISH Probe

The INSR-S1PR2 Fusion FISH Probe is used to confirm a fusion of the INSR and S1PR2 genes. The fusion of the INSR and S1PR2 genes has been associated with Stomach Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
INSR-S1PR2-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
INSR-S1PR2-20-RERE 20 (40 μL) 200 μL
INSR-S1PR2-20-REOR 20 (40 μL) 200 μL
INSR-S1PR2-20-REGO 20 (40 μL) 200 μL
INSR-S1PR2-20-REGR 20 (40 μL) 200 μL
INSR-S1PR2-20-REAQ 20 (40 μL) 200 μL
INSR-S1PR2-20-ORRE 20 (40 μL) 200 μL
INSR-S1PR2-20-OROR 20 (40 μL) 200 μL
INSR-S1PR2-20-ORGO 20 (40 μL) 200 μL
INSR-S1PR2-20-ORAQ 20 (40 μL) 200 μL
INSR-S1PR2-20-GORE 20 (40 μL) 200 μL
INSR-S1PR2-20-GOOR 20 (40 μL) 200 μL
INSR-S1PR2-20-GOGO 20 (40 μL) 200 μL
INSR-S1PR2-20-GOGR 20 (40 μL) 200 μL
INSR-S1PR2-20-GOAQ 20 (40 μL) 200 μL
INSR-S1PR2-20-GRRE 20 (40 μL) 200 μL
INSR-S1PR2-20-GROR 20 (40 μL) 200 μL
INSR-S1PR2-20-GRGO 20 (40 μL) 200 μL
INSR-S1PR2-20-GRGR 20 (40 μL) 200 μL
INSR-S1PR2-20-GRAQ 20 (40 μL) 200 μL
INSR-S1PR2-20-AQRE 20 (40 μL) 200 μL
INSR-S1PR2-20-AQOR 20 (40 μL) 200 μL
INSR-S1PR2-20-AQGO 20 (40 μL) 200 μL
INSR-S1PR2-20-AQGR 20 (40 μL) 200 μL
INSR-S1PR2-20-AQAQ 20 (40 μL) 200 μL

INSR Gene Summary

This gene encodes a member of the receptor tyrosine kinase family of proteins. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form a heterotetrameric receptor. Binding of insulin or other ligands to this receptor activates the insulin signaling pathway, which regulates glucose uptake and release, as well as the synthesis and storage of carbohydrates, lipids and protein. Mutations in this gene underlie the inherited severe insulin resistance syndromes including type A insulin resistance syndrome, Donohue syndrome and Rabson-Mendenhall syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015]

Gene Name: Insulin Receptor

Chromosome: CHR19: 7112265 -7294011

Locus: 19p13.2

S1PR2 Gene Summary

This gene encodes a member of the G protein-coupled receptors, as well as the EDG family of proteins. The encoded protein is a receptor for sphingosine 1-phosphate, which participates in cell proliferation, survival, and transcriptional activation. Defects in this gene have been associated with congenital profound deafness. [provided by RefSeq, Mar 2016]

Gene Name: Sphingosine-1-phosphate Receptor 2

Chromosome: CHR19: 10332108 -10341948

Locus: 19p13.2

Gene Diseases

The INSR S1PR2 Fusion has been associated with the following diseases:

Disease Name
Stomach Adenocarcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.