ITSN2-NMT1 Fusion FISH Probe
The ITSN2-NMT1 Fusion FISH Probe is used to confirm a fusion of the ITSN2 and NMT1 genes. The fusion of the ITSN2 and NMT1 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ITSN2-NMT1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ITSN2-NMT1-20-RERE | 20 (40 μL) | 200 μL |
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| ITSN2-NMT1-20-REOR | 20 (40 μL) | 200 μL |
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| ITSN2-NMT1-20-REGO | 20 (40 μL) | 200 μL |
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| ITSN2-NMT1-20-REGR | 20 (40 μL) | 200 μL |
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| ITSN2-NMT1-20-REAQ | 20 (40 μL) | 200 μL |
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| ITSN2-NMT1-20-ORRE | 20 (40 μL) | 200 μL |
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| ITSN2-NMT1-20-OROR | 20 (40 μL) | 200 μL |
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| ITSN2-NMT1-20-ORGO | 20 (40 μL) | 200 μL |
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| ITSN2-NMT1-20-ORAQ | 20 (40 μL) | 200 μL |
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| ITSN2-NMT1-20-GORE | 20 (40 μL) | 200 μL |
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| ITSN2-NMT1-20-GOOR | 20 (40 μL) | 200 μL |
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| ITSN2-NMT1-20-GOGO | 20 (40 μL) | 200 μL |
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| ITSN2-NMT1-20-GOGR | 20 (40 μL) | 200 μL |
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| ITSN2-NMT1-20-GOAQ | 20 (40 μL) | 200 μL |
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| ITSN2-NMT1-20-GRRE | 20 (40 μL) | 200 μL |
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| ITSN2-NMT1-20-GROR | 20 (40 μL) | 200 μL |
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| ITSN2-NMT1-20-GRGO | 20 (40 μL) | 200 μL |
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| ITSN2-NMT1-20-GRGR | 20 (40 μL) | 200 μL |
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| ITSN2-NMT1-20-GRAQ | 20 (40 μL) | 200 μL |
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| ITSN2-NMT1-20-AQRE | 20 (40 μL) | 200 μL |
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| ITSN2-NMT1-20-AQOR | 20 (40 μL) | 200 μL |
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| ITSN2-NMT1-20-AQGO | 20 (40 μL) | 200 μL |
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| ITSN2-NMT1-20-AQGR | 20 (40 μL) | 200 μL |
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| ITSN2-NMT1-20-AQAQ | 20 (40 μL) | 200 μL |
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NMT1 Gene Summary
Myristate, a rare 14-carbon saturated fatty acid, is cotranslationally attached by an amide linkage to the N-terminal glycine residue of cellular and viral proteins with diverse functions. N-myristoyltransferase (NMT; EC 2.3.1.97) catalyzes the transfer of myristate from CoA to proteins. N-myristoylation appears to be irreversible and is required for full expression of the biologic activities of several N-myristoylated proteins, including the alpha subunit of the signal-transducing guanine nucleotide-binding protein (G protein) GO (GNAO1; MIM 139311) (Duronio et al., 1992 [PubMed 1570339]).[supplied by OMIM, Nov 2008]
Gene Name: N-myristoyltransferase 1
Chromosome: CHR17: 43138679 -43186382
Locus: 17q21.31
ITSN2 Gene Summary
This gene encodes a cytoplasmic protein which contains SH3 domains. This protein is a member of a family of proteins involved in clathrin-mediated endocytosis. Intersectin 2 is thought to regulate the formation of clathrin-coated vesicles and also may function in the induction of T cell antigen receptor (TCR) endocytosis. [provided by RefSeq, Jan 2017]
Gene Name: Intersectin 2
Chromosome: CHR2: 24425734 -24583397
Locus: 2p23.3
Gene Diseases
The ITSN2 NMT1 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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