IYD-BIRC6 Fusion FISH Probe
The IYD-BIRC6 Fusion FISH Probe is used to confirm a fusion of the IYD and BIRC6 genes. The fusion of the IYD and BIRC6 genes has been associated with Thyroid Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| IYD-BIRC6-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| IYD-BIRC6-20-RERE | 20 (40 μL) | 200 μL |
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| IYD-BIRC6-20-REOR | 20 (40 μL) | 200 μL |
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| IYD-BIRC6-20-REGO | 20 (40 μL) | 200 μL |
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| IYD-BIRC6-20-REGR | 20 (40 μL) | 200 μL |
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| IYD-BIRC6-20-REAQ | 20 (40 μL) | 200 μL |
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| IYD-BIRC6-20-ORRE | 20 (40 μL) | 200 μL |
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| IYD-BIRC6-20-OROR | 20 (40 μL) | 200 μL |
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| IYD-BIRC6-20-ORGO | 20 (40 μL) | 200 μL |
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| IYD-BIRC6-20-ORAQ | 20 (40 μL) | 200 μL |
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| IYD-BIRC6-20-GORE | 20 (40 μL) | 200 μL |
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| IYD-BIRC6-20-GOOR | 20 (40 μL) | 200 μL |
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| IYD-BIRC6-20-GOGO | 20 (40 μL) | 200 μL |
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| IYD-BIRC6-20-GOGR | 20 (40 μL) | 200 μL |
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| IYD-BIRC6-20-GOAQ | 20 (40 μL) | 200 μL |
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| IYD-BIRC6-20-GRRE | 20 (40 μL) | 200 μL |
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| IYD-BIRC6-20-GROR | 20 (40 μL) | 200 μL |
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| IYD-BIRC6-20-GRGO | 20 (40 μL) | 200 μL |
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| IYD-BIRC6-20-GRGR | 20 (40 μL) | 200 μL |
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| IYD-BIRC6-20-GRAQ | 20 (40 μL) | 200 μL |
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| IYD-BIRC6-20-AQRE | 20 (40 μL) | 200 μL |
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| IYD-BIRC6-20-AQOR | 20 (40 μL) | 200 μL |
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| IYD-BIRC6-20-AQGO | 20 (40 μL) | 200 μL |
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| IYD-BIRC6-20-AQGR | 20 (40 μL) | 200 μL |
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| IYD-BIRC6-20-AQAQ | 20 (40 μL) | 200 μL |
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BIRC6 Gene Summary
This gene encodes a protein with a BIR (baculoviral inhibition of apoptosis protein repeat) domain and a UBCc (ubiquitin-conjugating enzyme E2, catalytic) domain. This protein inhibits apoptosis by facilitating the degradation of apoptotic proteins by ubiquitination. [provided by RefSeq, Jul 2008]
Gene Name: Baculoviral IAP Repeat Containing 6
Chromosome: CHR2: 32582095 -32843965
Locus: 2p22.3
IYD Gene Summary
This gene encodes an enzyme that catalyzes the oxidative NADPH-dependent deiodination of mono- and diiodotyrosine, which are the halogenated byproducts of thyroid hormone production. The N-terminus of the protein functions as a membrane anchor. Mutations in this gene cause congenital hypothyroidism due to dyshormonogenesis type 4, which is also referred to as deiodinase deficiency, or iodotyrosine dehalogenase deficiency, or thyroid hormonogenesis type 4. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009]
Gene Name: Iodotyrosine Deiodinase
Chromosome: CHR6: 150690027 -150725765
Locus: 6q25.1
Gene Diseases
The IYD BIRC6 Fusion has been associated with the following diseases:
| Disease Name |
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| Thyroid Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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