KCNC3-PRKDC Fusion FISH Probe
The KCNC3-PRKDC Fusion FISH Probe is used to confirm a fusion of the KCNC3 and PRKDC genes. The fusion of the KCNC3 and PRKDC genes has been associated with Cervical Squamous Cell Carcinoma And Endocervical Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| KCNC3-PRKDC-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| KCNC3-PRKDC-20-RERE | 20 (40 μL) | 200 μL |
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| KCNC3-PRKDC-20-REOR | 20 (40 μL) | 200 μL |
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| KCNC3-PRKDC-20-REGO | 20 (40 μL) | 200 μL |
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| KCNC3-PRKDC-20-REGR | 20 (40 μL) | 200 μL |
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| KCNC3-PRKDC-20-REAQ | 20 (40 μL) | 200 μL |
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| KCNC3-PRKDC-20-ORRE | 20 (40 μL) | 200 μL |
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| KCNC3-PRKDC-20-OROR | 20 (40 μL) | 200 μL |
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| KCNC3-PRKDC-20-ORGO | 20 (40 μL) | 200 μL |
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| KCNC3-PRKDC-20-ORAQ | 20 (40 μL) | 200 μL |
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| KCNC3-PRKDC-20-GORE | 20 (40 μL) | 200 μL |
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| KCNC3-PRKDC-20-GOOR | 20 (40 μL) | 200 μL |
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| KCNC3-PRKDC-20-GOGO | 20 (40 μL) | 200 μL |
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| KCNC3-PRKDC-20-GOGR | 20 (40 μL) | 200 μL |
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| KCNC3-PRKDC-20-GOAQ | 20 (40 μL) | 200 μL |
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| KCNC3-PRKDC-20-GRRE | 20 (40 μL) | 200 μL |
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| KCNC3-PRKDC-20-GROR | 20 (40 μL) | 200 μL |
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| KCNC3-PRKDC-20-GRGO | 20 (40 μL) | 200 μL |
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| KCNC3-PRKDC-20-GRGR | 20 (40 μL) | 200 μL |
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| KCNC3-PRKDC-20-GRAQ | 20 (40 μL) | 200 μL |
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| KCNC3-PRKDC-20-AQRE | 20 (40 μL) | 200 μL |
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| KCNC3-PRKDC-20-AQOR | 20 (40 μL) | 200 μL |
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| KCNC3-PRKDC-20-AQGO | 20 (40 μL) | 200 μL |
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| KCNC3-PRKDC-20-AQGR | 20 (40 μL) | 200 μL |
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| KCNC3-PRKDC-20-AQAQ | 20 (40 μL) | 200 μL |
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KCNC3 Gene Summary
The Shaker gene family of Drosophila encodes components of voltage-gated potassium channels and is comprised of four subfamilies. Based on sequence similarity, this gene is similar to one of these subfamilies, namely the Shaw subfamily. The protein encoded by this gene belongs to the delayed rectifier class of channel proteins and is an integral membrane protein that mediates the voltage-dependent potassium ion permeability of excitable membranes. Alternate splicing results in several transcript variants. [provided by RefSeq, Mar 2014]
Gene Name: Potassium Voltage-gated Channel Subfamily C Member 3
Chromosome: CHR19: 50818764 -50832634
Locus: 19q13.33
PRKDC Gene Summary
This gene encodes the catalytic subunit of the DNA-dependent protein kinase (DNA-PK). It functions with the Ku70/Ku80 heterodimer protein in DNA double strand break repair and recombination. The protein encoded is a member of the PI3/PI4-kinase family.[provided by RefSeq, Jul 2010]
Gene Name: Protein Kinase, DNA-activated, Catalytic Polypeptide
Chromosome: CHR8: 48685668 -48872743
Locus: 8q11.21
Gene Diseases
The KCNC3 PRKDC Fusion has been associated with the following diseases:
| Disease Name |
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| Cervical Squamous Cell Carcinoma And Endocervical Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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