KCNK5-KIF6 Fusion FISH Probe
The KCNK5-KIF6 Fusion FISH Probe is used to confirm a fusion of the KCNK5 and KIF6 genes. The fusion of the KCNK5 and KIF6 genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| KCNK5-KIF6-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| KCNK5-KIF6-20-RERE | 20 (40 μL) | 200 μL |
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| KCNK5-KIF6-20-REOR | 20 (40 μL) | 200 μL |
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| KCNK5-KIF6-20-REGO | 20 (40 μL) | 200 μL |
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| KCNK5-KIF6-20-REGR | 20 (40 μL) | 200 μL |
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| KCNK5-KIF6-20-REAQ | 20 (40 μL) | 200 μL |
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| KCNK5-KIF6-20-ORRE | 20 (40 μL) | 200 μL |
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| KCNK5-KIF6-20-OROR | 20 (40 μL) | 200 μL |
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| KCNK5-KIF6-20-ORGO | 20 (40 μL) | 200 μL |
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| KCNK5-KIF6-20-ORAQ | 20 (40 μL) | 200 μL |
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| KCNK5-KIF6-20-GORE | 20 (40 μL) | 200 μL |
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| KCNK5-KIF6-20-GOOR | 20 (40 μL) | 200 μL |
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| KCNK5-KIF6-20-GOGO | 20 (40 μL) | 200 μL |
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| KCNK5-KIF6-20-GOGR | 20 (40 μL) | 200 μL |
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| KCNK5-KIF6-20-GOAQ | 20 (40 μL) | 200 μL |
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| KCNK5-KIF6-20-GRRE | 20 (40 μL) | 200 μL |
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| KCNK5-KIF6-20-GROR | 20 (40 μL) | 200 μL |
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| KCNK5-KIF6-20-GRGO | 20 (40 μL) | 200 μL |
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| KCNK5-KIF6-20-GRGR | 20 (40 μL) | 200 μL |
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| KCNK5-KIF6-20-GRAQ | 20 (40 μL) | 200 μL |
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| KCNK5-KIF6-20-AQRE | 20 (40 μL) | 200 μL |
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| KCNK5-KIF6-20-AQOR | 20 (40 μL) | 200 μL |
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| KCNK5-KIF6-20-AQGO | 20 (40 μL) | 200 μL |
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| KCNK5-KIF6-20-AQGR | 20 (40 μL) | 200 μL |
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| KCNK5-KIF6-20-AQAQ | 20 (40 μL) | 200 μL |
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KCNK5 Gene Summary
This gene encodes one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. The message for this gene is mainly expressed in the cortical distal tubules and collecting ducts of the kidney. The protein is highly sensitive to external pH and this, in combination with its expression pattern, suggests it may play an important role in renal potassium transport. [provided by RefSeq, Jul 2008]
Gene Name: Potassium Two Pore Domain Channel Subfamily K Member 5
Chromosome: CHR6: 39156746 -39197251
Locus: 6p21.2
KIF6 Gene Summary
This gene encodes a member of a family of molecular motors which are involved in intracellular transport of protein complexes, membrane organelles, and messenger ribonucleic acid along microtubules. Kinesins function as homodimeric molecules with two N-terminal head domains that move along microtubules and two C-terminal tail domains that interact with the transported cargo, either directly or indirectly, through adapter molecules. This gene is ubiquitously expressed in coronary arteries and other vascular tissue. A naturally occurring mutation in this gene is associated with coronary heart disease. [provided by RefSeq, May 2017]
Gene Name: Kinesin Family Member 6
Chromosome: CHR6: 39302875 -39693181
Locus: 6p21.2
Gene Diseases
The KCNK5 KIF6 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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