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KCNMA1-MSMB Fusion FISH Probe

The KCNMA1-MSMB Fusion FISH Probe is used to confirm a fusion of the KCNMA1 and MSMB genes. The fusion of the KCNMA1 and MSMB genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
KCNMA1-MSMB-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
KCNMA1-MSMB-20-RERE 20 (40 μL) 200 μL
KCNMA1-MSMB-20-REOR 20 (40 μL) 200 μL
KCNMA1-MSMB-20-REGO 20 (40 μL) 200 μL
KCNMA1-MSMB-20-REGR 20 (40 μL) 200 μL
KCNMA1-MSMB-20-REAQ 20 (40 μL) 200 μL
KCNMA1-MSMB-20-ORRE 20 (40 μL) 200 μL
KCNMA1-MSMB-20-OROR 20 (40 μL) 200 μL
KCNMA1-MSMB-20-ORGO 20 (40 μL) 200 μL
KCNMA1-MSMB-20-ORAQ 20 (40 μL) 200 μL
KCNMA1-MSMB-20-GORE 20 (40 μL) 200 μL
KCNMA1-MSMB-20-GOOR 20 (40 μL) 200 μL
KCNMA1-MSMB-20-GOGO 20 (40 μL) 200 μL
KCNMA1-MSMB-20-GOGR 20 (40 μL) 200 μL
KCNMA1-MSMB-20-GOAQ 20 (40 μL) 200 μL
KCNMA1-MSMB-20-GRRE 20 (40 μL) 200 μL
KCNMA1-MSMB-20-GROR 20 (40 μL) 200 μL
KCNMA1-MSMB-20-GRGO 20 (40 μL) 200 μL
KCNMA1-MSMB-20-GRGR 20 (40 μL) 200 μL
KCNMA1-MSMB-20-GRAQ 20 (40 μL) 200 μL
KCNMA1-MSMB-20-AQRE 20 (40 μL) 200 μL
KCNMA1-MSMB-20-AQOR 20 (40 μL) 200 μL
KCNMA1-MSMB-20-AQGO 20 (40 μL) 200 μL
KCNMA1-MSMB-20-AQGR 20 (40 μL) 200 μL
KCNMA1-MSMB-20-AQAQ 20 (40 μL) 200 μL

KCNMA1 Gene Summary

MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit, which is the product of this gene, and the modulatory beta subunit. Intracellular calcium regulates the physical association between the alpha and beta subunits. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]

Gene Name: Potassium Calcium-activated Channel Subfamily M Alpha 1

Chromosome: CHR10: 78629358 -79397577

Locus: 10q22.3

MSMB Gene Summary

The protein encoded by this gene is a member of the immunoglobulin binding factor family. It is synthesized by the epithelial cells of the prostate gland and secreted into the seminal plasma. This protein has inhibin-like activity. It may have a role as an autocrine paracrine factor in uterine, breast and other female reproductive tissues. The expression of the encoded protein is found to be decreased in prostate cancer. Two alternatively spliced transcript variants encoding different isoforms are described for this gene. The use of alternate polyadenylation sites has been found for this gene. [provided by RefSeq, Jul 2008]

Gene Name: Microseminoprotein Beta

Chromosome: CHR10: 51549552 -51562518

Locus: 10q11.22

Gene Diseases

The KCNMA1 MSMB Fusion has been associated with the following diseases:

Disease Name
Breast Invasive Carcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.