KCNMB4-GLIPR1L2 Fusion FISH Probe
The KCNMB4-GLIPR1L2 Fusion FISH Probe is used to confirm a fusion of the KCNMB4 and GLIPR1L2 genes. The fusion of the KCNMB4 and GLIPR1L2 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| KCNMB4-GLIPR1L2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| KCNMB4-GLIPR1L2-20-RERE | 20 (40 μL) | 200 μL |
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| KCNMB4-GLIPR1L2-20-REOR | 20 (40 μL) | 200 μL |
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| KCNMB4-GLIPR1L2-20-REGO | 20 (40 μL) | 200 μL |
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| KCNMB4-GLIPR1L2-20-REGR | 20 (40 μL) | 200 μL |
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| KCNMB4-GLIPR1L2-20-REAQ | 20 (40 μL) | 200 μL |
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| KCNMB4-GLIPR1L2-20-ORRE | 20 (40 μL) | 200 μL |
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| KCNMB4-GLIPR1L2-20-OROR | 20 (40 μL) | 200 μL |
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| KCNMB4-GLIPR1L2-20-ORGO | 20 (40 μL) | 200 μL |
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| KCNMB4-GLIPR1L2-20-ORAQ | 20 (40 μL) | 200 μL |
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| KCNMB4-GLIPR1L2-20-GORE | 20 (40 μL) | 200 μL |
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| KCNMB4-GLIPR1L2-20-GOOR | 20 (40 μL) | 200 μL |
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| KCNMB4-GLIPR1L2-20-GOGO | 20 (40 μL) | 200 μL |
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| KCNMB4-GLIPR1L2-20-GOGR | 20 (40 μL) | 200 μL |
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| KCNMB4-GLIPR1L2-20-GOAQ | 20 (40 μL) | 200 μL |
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| KCNMB4-GLIPR1L2-20-GRRE | 20 (40 μL) | 200 μL |
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| KCNMB4-GLIPR1L2-20-GROR | 20 (40 μL) | 200 μL |
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| KCNMB4-GLIPR1L2-20-GRGO | 20 (40 μL) | 200 μL |
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| KCNMB4-GLIPR1L2-20-GRGR | 20 (40 μL) | 200 μL |
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| KCNMB4-GLIPR1L2-20-GRAQ | 20 (40 μL) | 200 μL |
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| KCNMB4-GLIPR1L2-20-AQRE | 20 (40 μL) | 200 μL |
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| KCNMB4-GLIPR1L2-20-AQOR | 20 (40 μL) | 200 μL |
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| KCNMB4-GLIPR1L2-20-AQGO | 20 (40 μL) | 200 μL |
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| KCNMB4-GLIPR1L2-20-AQGR | 20 (40 μL) | 200 μL |
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| KCNMB4-GLIPR1L2-20-AQAQ | 20 (40 μL) | 200 μL |
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KCNMB4 Gene Summary
MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit and the modulatory beta subunit. The protein encoded by this gene is an auxiliary beta subunit which slows activation kinetics, leads to steeper calcium sensitivity, and shifts the voltage range of current activation to more negative potentials than does the beta 1 subunit. [provided by RefSeq, Jul 2008]
Gene Name: Potassium Calcium-activated Channel Subfamily M Regulatory Beta Subunit 4
Chromosome: CHR12: 70760061 -70828072
Locus: 12q15
GLIPR1L2 Gene Summary
This gene encodes a member of the cysteine-rich secretory protein, antigen 5, and pathogenesis-related 1 superfamily. Members of this family have roles in a variety of processes, including cancer and immune defense. This gene is located in a cluster with two related genes on chromosome 12. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2012]
Gene Name: GLI Pathogenesis Related 1 Like 2
Chromosome: CHR12: 75784888 -75817820
Locus: 12q21.2
Gene Diseases
The KCNMB4 GLIPR1L2 Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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