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KCNQ3-ZHX2 Fusion FISH Probe

The KCNQ3-ZHX2 Fusion FISH Probe is used to confirm a fusion of the KCNQ3 and ZHX2 genes. The fusion of the KCNQ3 and ZHX2 genes has been associated with Thymoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
KCNQ3-ZHX2-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
KCNQ3-ZHX2-20-RERE 20 (40 μL) 200 μL
KCNQ3-ZHX2-20-REOR 20 (40 μL) 200 μL
KCNQ3-ZHX2-20-REGO 20 (40 μL) 200 μL
KCNQ3-ZHX2-20-REGR 20 (40 μL) 200 μL
KCNQ3-ZHX2-20-REAQ 20 (40 μL) 200 μL
KCNQ3-ZHX2-20-ORRE 20 (40 μL) 200 μL
KCNQ3-ZHX2-20-OROR 20 (40 μL) 200 μL
KCNQ3-ZHX2-20-ORGO 20 (40 μL) 200 μL
KCNQ3-ZHX2-20-ORAQ 20 (40 μL) 200 μL
KCNQ3-ZHX2-20-GORE 20 (40 μL) 200 μL
KCNQ3-ZHX2-20-GOOR 20 (40 μL) 200 μL
KCNQ3-ZHX2-20-GOGO 20 (40 μL) 200 μL
KCNQ3-ZHX2-20-GOGR 20 (40 μL) 200 μL
KCNQ3-ZHX2-20-GOAQ 20 (40 μL) 200 μL
KCNQ3-ZHX2-20-GRRE 20 (40 μL) 200 μL
KCNQ3-ZHX2-20-GROR 20 (40 μL) 200 μL
KCNQ3-ZHX2-20-GRGO 20 (40 μL) 200 μL
KCNQ3-ZHX2-20-GRGR 20 (40 μL) 200 μL
KCNQ3-ZHX2-20-GRAQ 20 (40 μL) 200 μL
KCNQ3-ZHX2-20-AQRE 20 (40 μL) 200 μL
KCNQ3-ZHX2-20-AQOR 20 (40 μL) 200 μL
KCNQ3-ZHX2-20-AQGO 20 (40 μL) 200 μL
KCNQ3-ZHX2-20-AQGR 20 (40 μL) 200 μL
KCNQ3-ZHX2-20-AQAQ 20 (40 μL) 200 μL

KCNQ3 Gene Summary

This gene encodes a protein that functions in the regulation of neuronal excitability. The encoded protein forms an M-channel by associating with the products of the related KCNQ2 or KCNQ5 genes, which both encode integral membrane proteins. M-channel currents are inhibited by M1 muscarinic acetylcholine receptors and are activated by retigabine, a novel anti-convulsant drug. Defects in this gene are a cause of benign familial neonatal convulsions type 2 (BFNC2), also known as epilepsy, benign neonatal type 2 (EBN2). Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, May 2014]

Gene Name: Potassium Voltage-gated Channel Subfamily Q Member 3

Chromosome: CHR8: 133133104 -133493004

Locus: 8q24.22

ZHX2 Gene Summary

The members of the zinc fingers and homeoboxes gene family are nuclear homodimeric transcriptional repressors that interact with the A subunit of nuclear factor-Y (NF-YA) and contain two C2H2-type zinc fingers and five homeobox DNA-binding domains. This gene encodes member 2 of this gene family. In addition to forming homodimers, this protein heterodimerizes with member 1 of the zinc fingers and homeoboxes family. [provided by RefSeq, Jul 2008]

Gene Name: Zinc Fingers And Homeoboxes 2

Chromosome: CHR8: 123793900 -123986755

Locus: 8q24.13

Gene Diseases

The KCNQ3 ZHX2 Fusion has been associated with the following diseases:

Disease Name
Thymoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.