KCTD7-KLK3 Fusion FISH Probe
The KCTD7-KLK3 Fusion FISH Probe is used to confirm a fusion of the KCTD7 and KLK3 genes. The fusion of the KCTD7 and KLK3 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| KCTD7-KLK3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| KCTD7-KLK3-20-RERE | 20 (40 μL) | 200 μL |
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| KCTD7-KLK3-20-REOR | 20 (40 μL) | 200 μL |
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| KCTD7-KLK3-20-REGO | 20 (40 μL) | 200 μL |
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| KCTD7-KLK3-20-REGR | 20 (40 μL) | 200 μL |
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| KCTD7-KLK3-20-REAQ | 20 (40 μL) | 200 μL |
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| KCTD7-KLK3-20-ORRE | 20 (40 μL) | 200 μL |
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| KCTD7-KLK3-20-OROR | 20 (40 μL) | 200 μL |
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| KCTD7-KLK3-20-ORGO | 20 (40 μL) | 200 μL |
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| KCTD7-KLK3-20-ORAQ | 20 (40 μL) | 200 μL |
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| KCTD7-KLK3-20-GORE | 20 (40 μL) | 200 μL |
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| KCTD7-KLK3-20-GOOR | 20 (40 μL) | 200 μL |
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| KCTD7-KLK3-20-GOGO | 20 (40 μL) | 200 μL |
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| KCTD7-KLK3-20-GOGR | 20 (40 μL) | 200 μL |
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| KCTD7-KLK3-20-GOAQ | 20 (40 μL) | 200 μL |
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| KCTD7-KLK3-20-GRRE | 20 (40 μL) | 200 μL |
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| KCTD7-KLK3-20-GROR | 20 (40 μL) | 200 μL |
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| KCTD7-KLK3-20-GRGO | 20 (40 μL) | 200 μL |
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| KCTD7-KLK3-20-GRGR | 20 (40 μL) | 200 μL |
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| KCTD7-KLK3-20-GRAQ | 20 (40 μL) | 200 μL |
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| KCTD7-KLK3-20-AQRE | 20 (40 μL) | 200 μL |
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| KCTD7-KLK3-20-AQOR | 20 (40 μL) | 200 μL |
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| KCTD7-KLK3-20-AQGO | 20 (40 μL) | 200 μL |
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| KCTD7-KLK3-20-AQGR | 20 (40 μL) | 200 μL |
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| KCTD7-KLK3-20-AQAQ | 20 (40 μL) | 200 μL |
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KLK3 Gene Summary
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its protein product is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates several transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Gene Name: Kallikrein Related Peptidase 3
Chromosome: CHR19: 51358170 -51364020
Locus: 19q13.33
KCTD7 Gene Summary
This gene encodes a member of the potassium channel tetramerization domain-containing protein family. Family members are identified on a structural basis and contain an amino-terminal domain similar to the T1 domain present in the voltage-gated potassium channel. Mutations in this gene have been associated with progressive myoclonic epilepsy-3. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Jan 2011]
Gene Name: Potassium Channel Tetramerization Domain Containing 7
Chromosome: CHR7: 66093867 -66108216
Locus: 7q11.21
Gene Diseases
The KCTD7 KLK3 Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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