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KDM5A-IQSEC3 Fusion FISH Probe

The KDM5A-IQSEC3 Fusion FISH Probe is used to confirm a fusion of the KDM5A and IQSEC3 genes. The fusion of the KDM5A and IQSEC3 genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
KDM5A-IQSEC3-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
KDM5A-IQSEC3-20-RERE 20 (40 μL) 200 μL
KDM5A-IQSEC3-20-REOR 20 (40 μL) 200 μL
KDM5A-IQSEC3-20-REGO 20 (40 μL) 200 μL
KDM5A-IQSEC3-20-REGR 20 (40 μL) 200 μL
KDM5A-IQSEC3-20-REAQ 20 (40 μL) 200 μL
KDM5A-IQSEC3-20-ORRE 20 (40 μL) 200 μL
KDM5A-IQSEC3-20-OROR 20 (40 μL) 200 μL
KDM5A-IQSEC3-20-ORGO 20 (40 μL) 200 μL
KDM5A-IQSEC3-20-ORAQ 20 (40 μL) 200 μL
KDM5A-IQSEC3-20-GORE 20 (40 μL) 200 μL
KDM5A-IQSEC3-20-GOOR 20 (40 μL) 200 μL
KDM5A-IQSEC3-20-GOGO 20 (40 μL) 200 μL
KDM5A-IQSEC3-20-GOGR 20 (40 μL) 200 μL
KDM5A-IQSEC3-20-GOAQ 20 (40 μL) 200 μL
KDM5A-IQSEC3-20-GRRE 20 (40 μL) 200 μL
KDM5A-IQSEC3-20-GROR 20 (40 μL) 200 μL
KDM5A-IQSEC3-20-GRGO 20 (40 μL) 200 μL
KDM5A-IQSEC3-20-GRGR 20 (40 μL) 200 μL
KDM5A-IQSEC3-20-GRAQ 20 (40 μL) 200 μL
KDM5A-IQSEC3-20-AQRE 20 (40 μL) 200 μL
KDM5A-IQSEC3-20-AQOR 20 (40 μL) 200 μL
KDM5A-IQSEC3-20-AQGO 20 (40 μL) 200 μL
KDM5A-IQSEC3-20-AQGR 20 (40 μL) 200 μL
KDM5A-IQSEC3-20-AQAQ 20 (40 μL) 200 μL

KDM5A Gene Summary

This gene encodes a member of the Jumonji, AT-rich interactive domain 1 (JARID1) histone demethylase protein family. The encoded protein plays a role in gene regulation through the histone code by specifically demethylating lysine 4 of histone H3. The encoded protein interacts with many other proteins, including retinoblastoma protein, and is implicated in the transcriptional regulation of Hox genes and cytokines. This gene may play a role in tumor progression. [provided by RefSeq, Aug 2013]

Gene Name: Lysine Demethylase 5A

Chromosome: CHR12: 389222 -498620

Locus: 12p13.33

IQSEC3 Gene Summary

The IQ Motif And Sec7 Domain 3 (IQSEC3) gene is located on chr12 :176048-287625 at 12p13.33.

Gene Name: IQ Motif And Sec7 Domain 3

Chromosome: CHR12: 176048 -287625

Locus: 12p13.33

Gene Diseases

The KDM5A IQSEC3 Fusion has been associated with the following diseases:

Disease Name
Skin Cutaneous Melanoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.