KDM5C-PPP4R1 Fusion FISH Probe
The KDM5C-PPP4R1 Fusion FISH Probe is used to confirm a fusion of the KDM5C and PPP4R1 genes. The fusion of the KDM5C and PPP4R1 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| KDM5C-PPP4R1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| KDM5C-PPP4R1-20-RERE | 20 (40 μL) | 200 μL |
|
|
| KDM5C-PPP4R1-20-REOR | 20 (40 μL) | 200 μL |
|
|
| KDM5C-PPP4R1-20-REGO | 20 (40 μL) | 200 μL |
|
|
| KDM5C-PPP4R1-20-REGR | 20 (40 μL) | 200 μL |
|
|
| KDM5C-PPP4R1-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| KDM5C-PPP4R1-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| KDM5C-PPP4R1-20-OROR | 20 (40 μL) | 200 μL |
|
|
| KDM5C-PPP4R1-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| KDM5C-PPP4R1-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| KDM5C-PPP4R1-20-GORE | 20 (40 μL) | 200 μL |
|
|
| KDM5C-PPP4R1-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| KDM5C-PPP4R1-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| KDM5C-PPP4R1-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| KDM5C-PPP4R1-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| KDM5C-PPP4R1-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| KDM5C-PPP4R1-20-GROR | 20 (40 μL) | 200 μL |
|
|
| KDM5C-PPP4R1-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| KDM5C-PPP4R1-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| KDM5C-PPP4R1-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| KDM5C-PPP4R1-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| KDM5C-PPP4R1-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| KDM5C-PPP4R1-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| KDM5C-PPP4R1-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| KDM5C-PPP4R1-20-AQAQ | 20 (40 μL) | 200 μL |
|
KDM5C Gene Summary
This gene is a member of the SMCY homolog family and encodes a protein with one ARID domain, one JmjC domain, one JmjN domain and two PHD-type zinc fingers. The DNA-binding motifs suggest this protein is involved in the regulation of transcription and chromatin remodeling. Mutations in this gene have been associated with X-linked cognitive disability. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009]
Gene Name: Lysine Demethylase 5C
Chromosome: CHRX: 53220502 -53254604
Locus: Xp11.22
PPP4R1 Gene Summary
This gene encodes one of several alternate regulatory subunits of serine/threonine protein phosphatase 4 (PP4). The protein features multiple HEAT repeats. This protein forms a complex with PP4RC. This complex may have a distinct role from other PP4 complexes, including regulation of HDAC3 (Zhang et al., PMID: 15805470). There is also a transcribed pseudogene on chromosome 20. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2012]
Gene Name: Protein Phosphatase 4 Regulatory Subunit 1
Chromosome: CHR18: 9546791 -9614600
Locus: 18p11.22
Gene Diseases
The KDM5C PPP4R1 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|