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KDM6A-DMD Fusion FISH Probe

The KDM6A-DMD Fusion FISH Probe is used to confirm a fusion of the KDM6A and DMD genes. The fusion of the KDM6A and DMD genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
KDM6A-DMD-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
KDM6A-DMD-20-RERE 20 (40 μL) 200 μL
KDM6A-DMD-20-REOR 20 (40 μL) 200 μL
KDM6A-DMD-20-REGO 20 (40 μL) 200 μL
KDM6A-DMD-20-REGR 20 (40 μL) 200 μL
KDM6A-DMD-20-REAQ 20 (40 μL) 200 μL
KDM6A-DMD-20-ORRE 20 (40 μL) 200 μL
KDM6A-DMD-20-OROR 20 (40 μL) 200 μL
KDM6A-DMD-20-ORGO 20 (40 μL) 200 μL
KDM6A-DMD-20-ORAQ 20 (40 μL) 200 μL
KDM6A-DMD-20-GORE 20 (40 μL) 200 μL
KDM6A-DMD-20-GOOR 20 (40 μL) 200 μL
KDM6A-DMD-20-GOGO 20 (40 μL) 200 μL
KDM6A-DMD-20-GOGR 20 (40 μL) 200 μL
KDM6A-DMD-20-GOAQ 20 (40 μL) 200 μL
KDM6A-DMD-20-GRRE 20 (40 μL) 200 μL
KDM6A-DMD-20-GROR 20 (40 μL) 200 μL
KDM6A-DMD-20-GRGO 20 (40 μL) 200 μL
KDM6A-DMD-20-GRGR 20 (40 μL) 200 μL
KDM6A-DMD-20-GRAQ 20 (40 μL) 200 μL
KDM6A-DMD-20-AQRE 20 (40 μL) 200 μL
KDM6A-DMD-20-AQOR 20 (40 μL) 200 μL
KDM6A-DMD-20-AQGO 20 (40 μL) 200 μL
KDM6A-DMD-20-AQGR 20 (40 μL) 200 μL
KDM6A-DMD-20-AQAQ 20 (40 μL) 200 μL

DMD Gene Summary

This gene spans a genomic range of greater than 2 Mb and encodes a large protein containing an N-terminal actin-binding domain and multiple spectrin repeats. The encoded protein forms a component of the dystrophin-glycoprotein complex (DGC), which bridges the inner cytoskeleton and the extracellular matrix. Deletions, duplications, and point mutations at this gene locus may cause Duchenne muscular dystrophy (DMD), Becker muscular dystrophy (BMD), or cardiomyopathy. Alternative promoter usage and alternative splicing result in numerous distinct transcript variants and protein isoforms for this gene. [provided by RefSeq, Dec 2016]

Gene Name: Dystrophin

Chromosome: CHRX: 31137344 -33357726

Locus: Xp21.2-p21.1

KDM6A Gene Summary

This gene is located on the X chromosome and is the corresponding locus to a Y-linked gene which encodes a tetratricopeptide repeat (TPR) protein. The encoded protein of this gene contains a JmjC-domain and catalyzes the demethylation of tri/dimethylated histone H3. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Apr 2014]

Gene Name: Lysine Demethylase 6A

Chromosome: CHRX: 44732422 -44971845

Locus: Xp11.3

Gene Diseases

The KDM6A DMD Fusion has been associated with the following diseases:

Disease Name
Lung Adenocarcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.