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KDM6A-ZNF674 Fusion FISH Probe

The KDM6A-ZNF674 Fusion FISH Probe is used to confirm a fusion of the KDM6A and ZNF674 genes. The fusion of the KDM6A and ZNF674 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
KDM6A-ZNF674-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
KDM6A-ZNF674-20-RERE 20 (40 μL) 200 μL
KDM6A-ZNF674-20-REOR 20 (40 μL) 200 μL
KDM6A-ZNF674-20-REGO 20 (40 μL) 200 μL
KDM6A-ZNF674-20-REGR 20 (40 μL) 200 μL
KDM6A-ZNF674-20-REAQ 20 (40 μL) 200 μL
KDM6A-ZNF674-20-ORRE 20 (40 μL) 200 μL
KDM6A-ZNF674-20-OROR 20 (40 μL) 200 μL
KDM6A-ZNF674-20-ORGO 20 (40 μL) 200 μL
KDM6A-ZNF674-20-ORAQ 20 (40 μL) 200 μL
KDM6A-ZNF674-20-GORE 20 (40 μL) 200 μL
KDM6A-ZNF674-20-GOOR 20 (40 μL) 200 μL
KDM6A-ZNF674-20-GOGO 20 (40 μL) 200 μL
KDM6A-ZNF674-20-GOGR 20 (40 μL) 200 μL
KDM6A-ZNF674-20-GOAQ 20 (40 μL) 200 μL
KDM6A-ZNF674-20-GRRE 20 (40 μL) 200 μL
KDM6A-ZNF674-20-GROR 20 (40 μL) 200 μL
KDM6A-ZNF674-20-GRGO 20 (40 μL) 200 μL
KDM6A-ZNF674-20-GRGR 20 (40 μL) 200 μL
KDM6A-ZNF674-20-GRAQ 20 (40 μL) 200 μL
KDM6A-ZNF674-20-AQRE 20 (40 μL) 200 μL
KDM6A-ZNF674-20-AQOR 20 (40 μL) 200 μL
KDM6A-ZNF674-20-AQGO 20 (40 μL) 200 μL
KDM6A-ZNF674-20-AQGR 20 (40 μL) 200 μL
KDM6A-ZNF674-20-AQAQ 20 (40 μL) 200 μL

KDM6A Gene Summary

This gene is located on the X chromosome and is the corresponding locus to a Y-linked gene which encodes a tetratricopeptide repeat (TPR) protein. The encoded protein of this gene contains a JmjC-domain and catalyzes the demethylation of tri/dimethylated histone H3. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Apr 2014]

Gene Name: Lysine Demethylase 6A

Chromosome: CHRX: 44732422 -44971845

Locus: Xp11.3

ZNF674 Gene Summary

This gene encodes a zinc finger protein with an N-terminal Kruppel-associated box-containing (KRAB) domain and 11 Kruppel-type C2H2 zinc finger domains. Like other zinc finger proteins, this gene may function as a transcription factor. This gene resides on an area of chromosome X that has been implicated in nonsyndromic X-linked cognitive disabilities. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2017]

Gene Name: Zinc Finger Protein 674

Chromosome: CHRX: 46357159 -46404892

Locus: Xp11.3

Gene Diseases

The KDM6A ZNF674 Fusion has been associated with the following diseases:

Disease Name
Lung Adenocarcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.