KIAA0586-MPP5 Fusion FISH Probe
The KIAA0586-MPP5 Fusion FISH Probe is used to confirm a fusion of the KIAA0586 and MPP5 genes. The fusion of the KIAA0586 and MPP5 genes has been associated with Glioblastoma Multiforme. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| KIAA0586-MPP5-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| KIAA0586-MPP5-20-RERE | 20 (40 μL) | 200 μL |
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| KIAA0586-MPP5-20-REOR | 20 (40 μL) | 200 μL |
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| KIAA0586-MPP5-20-REGO | 20 (40 μL) | 200 μL |
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| KIAA0586-MPP5-20-REGR | 20 (40 μL) | 200 μL |
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| KIAA0586-MPP5-20-REAQ | 20 (40 μL) | 200 μL |
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| KIAA0586-MPP5-20-ORRE | 20 (40 μL) | 200 μL |
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| KIAA0586-MPP5-20-OROR | 20 (40 μL) | 200 μL |
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| KIAA0586-MPP5-20-ORGO | 20 (40 μL) | 200 μL |
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| KIAA0586-MPP5-20-ORAQ | 20 (40 μL) | 200 μL |
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| KIAA0586-MPP5-20-GORE | 20 (40 μL) | 200 μL |
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| KIAA0586-MPP5-20-GOOR | 20 (40 μL) | 200 μL |
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| KIAA0586-MPP5-20-GOGO | 20 (40 μL) | 200 μL |
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| KIAA0586-MPP5-20-GOGR | 20 (40 μL) | 200 μL |
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| KIAA0586-MPP5-20-GOAQ | 20 (40 μL) | 200 μL |
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| KIAA0586-MPP5-20-GRRE | 20 (40 μL) | 200 μL |
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| KIAA0586-MPP5-20-GROR | 20 (40 μL) | 200 μL |
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| KIAA0586-MPP5-20-GRGO | 20 (40 μL) | 200 μL |
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| KIAA0586-MPP5-20-GRGR | 20 (40 μL) | 200 μL |
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| KIAA0586-MPP5-20-GRAQ | 20 (40 μL) | 200 μL |
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| KIAA0586-MPP5-20-AQRE | 20 (40 μL) | 200 μL |
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| KIAA0586-MPP5-20-AQOR | 20 (40 μL) | 200 μL |
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| KIAA0586-MPP5-20-AQGO | 20 (40 μL) | 200 μL |
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| KIAA0586-MPP5-20-AQGR | 20 (40 μL) | 200 μL |
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| KIAA0586-MPP5-20-AQAQ | 20 (40 μL) | 200 μL |
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KIAA0586 Gene Summary
This gene encodes a conserved centrosomal protein that functions in ciliogenesis and responds to hedgehog signaling. Mutations in this gene causes Joubert syndrome 23. Alternative splicing results in multiple transcript variants and protein isoforms. [provided by RefSeq, Aug 2016]
Gene Name:
Chromosome: CHR14: 58894102 -59015549
Locus: 14q23.1
MPP5 Gene Summary
This gene encodes a member of the p55-like subfamily of the membrane-associated guanylate kinase (MAGUK) gene superfamily. The encoded protein participates in the polarization of differentiating cells, has been shown to regulate myelinating Schwann cells (PMID: 20237282), and is one of the components of the Crumbs complex in the retina. Mice which express lower levels of the orthologous protein have retinal degeneration and impaired vision (PMID: 22114289). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012]
Gene Name: Membrane Palmitoylated Protein 5
Chromosome: CHR14: 67708020 -67802536
Locus: 14q23.3
Gene Diseases
The KIAA0586 MPP5 Fusion has been associated with the following diseases:
| Disease Name |
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| Glioblastoma Multiforme |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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