KIF23-PIAS1 Fusion FISH Probe
The KIF23-PIAS1 Fusion FISH Probe is used to confirm a fusion of the KIF23 and PIAS1 genes. The fusion of the KIF23 and PIAS1 genes has been associated with Liver Hepatocellular Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| KIF23-PIAS1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| KIF23-PIAS1-20-RERE | 20 (40 μL) | 200 μL |
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| KIF23-PIAS1-20-REOR | 20 (40 μL) | 200 μL |
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| KIF23-PIAS1-20-REGO | 20 (40 μL) | 200 μL |
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| KIF23-PIAS1-20-REGR | 20 (40 μL) | 200 μL |
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| KIF23-PIAS1-20-REAQ | 20 (40 μL) | 200 μL |
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| KIF23-PIAS1-20-ORRE | 20 (40 μL) | 200 μL |
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| KIF23-PIAS1-20-OROR | 20 (40 μL) | 200 μL |
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| KIF23-PIAS1-20-ORGO | 20 (40 μL) | 200 μL |
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| KIF23-PIAS1-20-ORAQ | 20 (40 μL) | 200 μL |
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| KIF23-PIAS1-20-GORE | 20 (40 μL) | 200 μL |
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| KIF23-PIAS1-20-GOOR | 20 (40 μL) | 200 μL |
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| KIF23-PIAS1-20-GOGO | 20 (40 μL) | 200 μL |
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| KIF23-PIAS1-20-GOGR | 20 (40 μL) | 200 μL |
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| KIF23-PIAS1-20-GOAQ | 20 (40 μL) | 200 μL |
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| KIF23-PIAS1-20-GRRE | 20 (40 μL) | 200 μL |
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| KIF23-PIAS1-20-GROR | 20 (40 μL) | 200 μL |
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| KIF23-PIAS1-20-GRGO | 20 (40 μL) | 200 μL |
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| KIF23-PIAS1-20-GRGR | 20 (40 μL) | 200 μL |
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| KIF23-PIAS1-20-GRAQ | 20 (40 μL) | 200 μL |
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| KIF23-PIAS1-20-AQRE | 20 (40 μL) | 200 μL |
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| KIF23-PIAS1-20-AQOR | 20 (40 μL) | 200 μL |
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| KIF23-PIAS1-20-AQGO | 20 (40 μL) | 200 μL |
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| KIF23-PIAS1-20-AQGR | 20 (40 μL) | 200 μL |
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| KIF23-PIAS1-20-AQAQ | 20 (40 μL) | 200 μL |
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PIAS1 Gene Summary
This gene encodes a member of the protein inhibitor of activated STAT (PIAS) family. PIAS proteins function as SUMO E3 ligases and play important roles in many cellular processes by mediating the sumoylation of target proteins. This protein plays a central role as a transcriptional coregulator of numerous cellular pathways includign the STAT1 and nuclear factor kappaB pathways. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]
Gene Name: Protein Inhibitor Of Activated STAT 1
Chromosome: CHR15: 68346571 -68480404
Locus: 15q23
KIF23 Gene Summary
The protein encoded by this gene is a member of kinesin-like protein family. This family includes microtubule-dependent molecular motors that transport organelles within cells and move chromosomes during cell division. This protein has been shown to cross-bridge antiparallel microtubules and drive microtubule movement in vitro. Alternate splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2013]
Gene Name: Kinesin Family Member 23
Chromosome: CHR15: 69706626 -69740764
Locus: 15q23
Gene Diseases
The KIF23 PIAS1 Fusion has been associated with the following diseases:
| Disease Name |
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| Liver Hepatocellular Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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