KIF5C-STK39 Fusion FISH Probe
The KIF5C-STK39 Fusion FISH Probe is used to confirm a fusion of the KIF5C and STK39 genes. The fusion of the KIF5C and STK39 genes has been associated with Esophageal Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| KIF5C-STK39-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| KIF5C-STK39-20-RERE | 20 (40 μL) | 200 μL |
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| KIF5C-STK39-20-REOR | 20 (40 μL) | 200 μL |
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| KIF5C-STK39-20-REGO | 20 (40 μL) | 200 μL |
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| KIF5C-STK39-20-REGR | 20 (40 μL) | 200 μL |
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| KIF5C-STK39-20-REAQ | 20 (40 μL) | 200 μL |
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| KIF5C-STK39-20-ORRE | 20 (40 μL) | 200 μL |
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| KIF5C-STK39-20-OROR | 20 (40 μL) | 200 μL |
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| KIF5C-STK39-20-ORGO | 20 (40 μL) | 200 μL |
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| KIF5C-STK39-20-ORAQ | 20 (40 μL) | 200 μL |
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| KIF5C-STK39-20-GORE | 20 (40 μL) | 200 μL |
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| KIF5C-STK39-20-GOOR | 20 (40 μL) | 200 μL |
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| KIF5C-STK39-20-GOGO | 20 (40 μL) | 200 μL |
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| KIF5C-STK39-20-GOGR | 20 (40 μL) | 200 μL |
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| KIF5C-STK39-20-GOAQ | 20 (40 μL) | 200 μL |
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| KIF5C-STK39-20-GRRE | 20 (40 μL) | 200 μL |
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| KIF5C-STK39-20-GROR | 20 (40 μL) | 200 μL |
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| KIF5C-STK39-20-GRGO | 20 (40 μL) | 200 μL |
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| KIF5C-STK39-20-GRGR | 20 (40 μL) | 200 μL |
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| KIF5C-STK39-20-GRAQ | 20 (40 μL) | 200 μL |
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| KIF5C-STK39-20-AQRE | 20 (40 μL) | 200 μL |
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| KIF5C-STK39-20-AQOR | 20 (40 μL) | 200 μL |
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| KIF5C-STK39-20-AQGO | 20 (40 μL) | 200 μL |
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| KIF5C-STK39-20-AQGR | 20 (40 μL) | 200 μL |
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| KIF5C-STK39-20-AQAQ | 20 (40 μL) | 200 μL |
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KIF5C Gene Summary
The protein encoded by this gene is a kinesin heavy chain subunit involved in the transport of cargo within the central nervous system. The encoded protein, which acts as a tetramer by associating with another heavy chain and two light chains, interacts with protein kinase CK2. Mutations in this gene have been associated with complex cortical dysplasia with other brain malformations-2. Two transcript variants, one protein-coding and the other non-protein coding, have been found for this gene. [provided by RefSeq, Jul 2015]
Gene Name: Kinesin Family Member 5C
Chromosome: CHR2: 149632818 -149883273
Locus: 2q23.1-q23.2
STK39 Gene Summary
This gene encodes a serine/threonine kinase that is thought to function in the cellular stress response pathway. The kinase is activated in response to hypotonic stress, leading to phosphorylation of several cation-chloride-coupled cotransporters. The catalytically active kinase specifically activates the p38 MAP kinase pathway, and its interaction with p38 decreases upon cellular stress, suggesting that this kinase may serve as an intermediate in the response to cellular stress. [provided by RefSeq, Jul 2008]
Gene Name: Serine/threonine Kinase 39
Chromosome: CHR2: 168810529 -169104105
Locus: 2q24.3
Gene Diseases
The KIF5C STK39 Fusion has been associated with the following diseases:
| Disease Name |
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| Esophageal Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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