KLF7-PARD3B Fusion FISH Probe
The KLF7-PARD3B Fusion FISH Probe is used to confirm a fusion of the KLF7 and PARD3B genes. The fusion of the KLF7 and PARD3B genes has been associated with Lung Adenocarcinoma, and Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| KLF7-PARD3B-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| KLF7-PARD3B-20-RERE | 20 (40 μL) | 200 μL |
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| KLF7-PARD3B-20-REOR | 20 (40 μL) | 200 μL |
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| KLF7-PARD3B-20-REGO | 20 (40 μL) | 200 μL |
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| KLF7-PARD3B-20-REGR | 20 (40 μL) | 200 μL |
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| KLF7-PARD3B-20-REAQ | 20 (40 μL) | 200 μL |
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| KLF7-PARD3B-20-ORRE | 20 (40 μL) | 200 μL |
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| KLF7-PARD3B-20-OROR | 20 (40 μL) | 200 μL |
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| KLF7-PARD3B-20-ORGO | 20 (40 μL) | 200 μL |
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| KLF7-PARD3B-20-ORAQ | 20 (40 μL) | 200 μL |
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| KLF7-PARD3B-20-GORE | 20 (40 μL) | 200 μL |
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| KLF7-PARD3B-20-GOOR | 20 (40 μL) | 200 μL |
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| KLF7-PARD3B-20-GOGO | 20 (40 μL) | 200 μL |
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| KLF7-PARD3B-20-GOGR | 20 (40 μL) | 200 μL |
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| KLF7-PARD3B-20-GOAQ | 20 (40 μL) | 200 μL |
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| KLF7-PARD3B-20-GRRE | 20 (40 μL) | 200 μL |
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| KLF7-PARD3B-20-GROR | 20 (40 μL) | 200 μL |
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| KLF7-PARD3B-20-GRGO | 20 (40 μL) | 200 μL |
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| KLF7-PARD3B-20-GRGR | 20 (40 μL) | 200 μL |
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| KLF7-PARD3B-20-GRAQ | 20 (40 μL) | 200 μL |
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| KLF7-PARD3B-20-AQRE | 20 (40 μL) | 200 μL |
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| KLF7-PARD3B-20-AQOR | 20 (40 μL) | 200 μL |
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| KLF7-PARD3B-20-AQGO | 20 (40 μL) | 200 μL |
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| KLF7-PARD3B-20-AQGR | 20 (40 μL) | 200 μL |
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| KLF7-PARD3B-20-AQAQ | 20 (40 μL) | 200 μL |
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KLF7 Gene Summary
The protein encoded by this gene is a member of the Kruppel-like transcriptional regulator family. Members in this family regulate cell proliferation, differentiation and survival and contain three C2H2 zinc fingers at the C-terminus that mediate binding to GC-rich sites. This protein may contribute to the progression of type 2 diabetes by inhibiting insulin expression and secretion in pancreatic beta-cells and by deregulating adipocytokine secretion in adipocytes. A pseudogene of this gene is located on the long arm of chromosome 3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]
Gene Name: Kruppel Like Factor 7
Chromosome: CHR2: 207945528 -208030614
Locus: 2q33.3
PARD3B Gene Summary
The Par-3 Family Cell Polarity Regulator Beta (PARD3B) gene is located on chr2 :205410515-206484886 at 2q33.3.
Gene Name: Par-3 Family Cell Polarity Regulator Beta
Chromosome: CHR2: 205410515 -206484886
Locus: 2q33.3
Gene Diseases
The KLF7 PARD3B Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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