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KLF7-RFTN2 Fusion FISH Probe

The KLF7-RFTN2 Fusion FISH Probe is used to confirm a fusion of the KLF7 and RFTN2 genes. The fusion of the KLF7 and RFTN2 genes has been associated with Mesothelioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
KLF7-RFTN2-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
KLF7-RFTN2-20-RERE 20 (40 μL) 200 μL
KLF7-RFTN2-20-REOR 20 (40 μL) 200 μL
KLF7-RFTN2-20-REGO 20 (40 μL) 200 μL
KLF7-RFTN2-20-REGR 20 (40 μL) 200 μL
KLF7-RFTN2-20-REAQ 20 (40 μL) 200 μL
KLF7-RFTN2-20-ORRE 20 (40 μL) 200 μL
KLF7-RFTN2-20-OROR 20 (40 μL) 200 μL
KLF7-RFTN2-20-ORGO 20 (40 μL) 200 μL
KLF7-RFTN2-20-ORAQ 20 (40 μL) 200 μL
KLF7-RFTN2-20-GORE 20 (40 μL) 200 μL
KLF7-RFTN2-20-GOOR 20 (40 μL) 200 μL
KLF7-RFTN2-20-GOGO 20 (40 μL) 200 μL
KLF7-RFTN2-20-GOGR 20 (40 μL) 200 μL
KLF7-RFTN2-20-GOAQ 20 (40 μL) 200 μL
KLF7-RFTN2-20-GRRE 20 (40 μL) 200 μL
KLF7-RFTN2-20-GROR 20 (40 μL) 200 μL
KLF7-RFTN2-20-GRGO 20 (40 μL) 200 μL
KLF7-RFTN2-20-GRGR 20 (40 μL) 200 μL
KLF7-RFTN2-20-GRAQ 20 (40 μL) 200 μL
KLF7-RFTN2-20-AQRE 20 (40 μL) 200 μL
KLF7-RFTN2-20-AQOR 20 (40 μL) 200 μL
KLF7-RFTN2-20-AQGO 20 (40 μL) 200 μL
KLF7-RFTN2-20-AQGR 20 (40 μL) 200 μL
KLF7-RFTN2-20-AQAQ 20 (40 μL) 200 μL

KLF7 Gene Summary

The protein encoded by this gene is a member of the Kruppel-like transcriptional regulator family. Members in this family regulate cell proliferation, differentiation and survival and contain three C2H2 zinc fingers at the C-terminus that mediate binding to GC-rich sites. This protein may contribute to the progression of type 2 diabetes by inhibiting insulin expression and secretion in pancreatic beta-cells and by deregulating adipocytokine secretion in adipocytes. A pseudogene of this gene is located on the long arm of chromosome 3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]

Gene Name: Kruppel Like Factor 7

Chromosome: CHR2: 207945528 -208030614

Locus: 2q33.3

RFTN2 Gene Summary

The Raftlin Family Member 2 (RFTN2) gene is located on chr2 :198435526-198540584 at 2q33.1.

Gene Name: Raftlin Family Member 2

Chromosome: CHR2: 198435526 -198540584

Locus: 2q33.1

Gene Diseases

The KLF7 RFTN2 Fusion has been associated with the following diseases:

Disease Name
Mesothelioma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.