KLHL1-HNRNPF Fusion FISH Probe
The KLHL1-HNRNPF Fusion FISH Probe is used to confirm a fusion of the KLHL1 and HNRNPF genes. The fusion of the KLHL1 and HNRNPF genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| KLHL1-HNRNPF-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| KLHL1-HNRNPF-20-RERE | 20 (40 μL) | 200 μL |
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| KLHL1-HNRNPF-20-REOR | 20 (40 μL) | 200 μL |
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| KLHL1-HNRNPF-20-REGO | 20 (40 μL) | 200 μL |
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| KLHL1-HNRNPF-20-REGR | 20 (40 μL) | 200 μL |
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| KLHL1-HNRNPF-20-REAQ | 20 (40 μL) | 200 μL |
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| KLHL1-HNRNPF-20-ORRE | 20 (40 μL) | 200 μL |
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| KLHL1-HNRNPF-20-OROR | 20 (40 μL) | 200 μL |
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| KLHL1-HNRNPF-20-ORGO | 20 (40 μL) | 200 μL |
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| KLHL1-HNRNPF-20-ORAQ | 20 (40 μL) | 200 μL |
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| KLHL1-HNRNPF-20-GORE | 20 (40 μL) | 200 μL |
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| KLHL1-HNRNPF-20-GOOR | 20 (40 μL) | 200 μL |
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| KLHL1-HNRNPF-20-GOGO | 20 (40 μL) | 200 μL |
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| KLHL1-HNRNPF-20-GOGR | 20 (40 μL) | 200 μL |
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| KLHL1-HNRNPF-20-GOAQ | 20 (40 μL) | 200 μL |
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| KLHL1-HNRNPF-20-GRRE | 20 (40 μL) | 200 μL |
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| KLHL1-HNRNPF-20-GROR | 20 (40 μL) | 200 μL |
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| KLHL1-HNRNPF-20-GRGO | 20 (40 μL) | 200 μL |
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| KLHL1-HNRNPF-20-GRGR | 20 (40 μL) | 200 μL |
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| KLHL1-HNRNPF-20-GRAQ | 20 (40 μL) | 200 μL |
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| KLHL1-HNRNPF-20-AQRE | 20 (40 μL) | 200 μL |
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| KLHL1-HNRNPF-20-AQOR | 20 (40 μL) | 200 μL |
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| KLHL1-HNRNPF-20-AQGO | 20 (40 μL) | 200 μL |
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| KLHL1-HNRNPF-20-AQGR | 20 (40 μL) | 200 μL |
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| KLHL1-HNRNPF-20-AQAQ | 20 (40 μL) | 200 μL |
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HNRNPF Gene Summary
This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins that complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and regulate alternative splicing, polyadenylation, and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that bind to RNAs which have guanosine-rich sequences. This protein is very similar to the family member hnRPH. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]
Gene Name: Heterogeneous Nuclear Ribonucleoprotein F
Chromosome: CHR10: 43881064 -43904696
Locus: 10q11.21
KLHL1 Gene Summary
The KLHL1 protein belongs to a family of actin-organizing proteins related to Drosophila Kelch (Nemes et al., 2000 [PubMed 10888605]).[supplied by OMIM, Feb 2010]
Gene Name: Kelch Like Family Member 1
Chromosome: CHR13: 70274724 -70682625
Locus: 13q21.33
Gene Diseases
The KLHL1 HNRNPF Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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