LCOR-MAP2K6 Fusion FISH Probe
The LCOR-MAP2K6 Fusion FISH Probe is used to confirm a fusion of the LCOR and MAP2K6 genes. The fusion of the LCOR and MAP2K6 genes has been associated with Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| LCOR-MAP2K6-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| LCOR-MAP2K6-20-RERE | 20 (40 μL) | 200 μL |
|
|
| LCOR-MAP2K6-20-REOR | 20 (40 μL) | 200 μL |
|
|
| LCOR-MAP2K6-20-REGO | 20 (40 μL) | 200 μL |
|
|
| LCOR-MAP2K6-20-REGR | 20 (40 μL) | 200 μL |
|
|
| LCOR-MAP2K6-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| LCOR-MAP2K6-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| LCOR-MAP2K6-20-OROR | 20 (40 μL) | 200 μL |
|
|
| LCOR-MAP2K6-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| LCOR-MAP2K6-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| LCOR-MAP2K6-20-GORE | 20 (40 μL) | 200 μL |
|
|
| LCOR-MAP2K6-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| LCOR-MAP2K6-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| LCOR-MAP2K6-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| LCOR-MAP2K6-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| LCOR-MAP2K6-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| LCOR-MAP2K6-20-GROR | 20 (40 μL) | 200 μL |
|
|
| LCOR-MAP2K6-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| LCOR-MAP2K6-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| LCOR-MAP2K6-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| LCOR-MAP2K6-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| LCOR-MAP2K6-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| LCOR-MAP2K6-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| LCOR-MAP2K6-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| LCOR-MAP2K6-20-AQAQ | 20 (40 μL) | 200 μL |
|
MAP2K6 Gene Summary
This gene encodes a member of the dual specificity protein kinase family, which functions as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines or environmental stress. As an essential component of p38 MAP kinase mediated signal transduction pathway, this gene is involved in many cellular processes such as stress induced cell cycle arrest, transcription activation and apoptosis. [provided by RefSeq, Jul 2008]
Gene Name: Mitogen-activated Protein Kinase Kinase 6
Chromosome: CHR17: 67410837 -67538470
Locus: 17q24.3
LCOR Gene Summary
LCOR is a transcriptional corepressor widely expressed in fetal and adult tissues that is recruited to agonist-bound nuclear receptors through a single LxxLL motif, also referred to as a nuclear receptor (NR) box (Fernandes et al., 2003 [PubMed 12535528]).[supplied by OMIM, Mar 2008]
Gene Name: Ligand Dependent Nuclear Receptor Corepressor
Chromosome: CHR10: 98592016 -98724198
Locus: 10q24.1
Gene Diseases
The LCOR MAP2K6 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Bladder Urothelial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|