LETM2-ERCC2 Fusion FISH Probe
The LETM2-ERCC2 Fusion FISH Probe is used to confirm a fusion of the LETM2 and ERCC2 genes. The fusion of the LETM2 and ERCC2 genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| LETM2-ERCC2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| LETM2-ERCC2-20-RERE | 20 (40 μL) | 200 μL |
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| LETM2-ERCC2-20-REOR | 20 (40 μL) | 200 μL |
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| LETM2-ERCC2-20-REGO | 20 (40 μL) | 200 μL |
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| LETM2-ERCC2-20-REGR | 20 (40 μL) | 200 μL |
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| LETM2-ERCC2-20-REAQ | 20 (40 μL) | 200 μL |
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| LETM2-ERCC2-20-ORRE | 20 (40 μL) | 200 μL |
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| LETM2-ERCC2-20-OROR | 20 (40 μL) | 200 μL |
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| LETM2-ERCC2-20-ORGO | 20 (40 μL) | 200 μL |
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| LETM2-ERCC2-20-ORAQ | 20 (40 μL) | 200 μL |
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| LETM2-ERCC2-20-GORE | 20 (40 μL) | 200 μL |
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| LETM2-ERCC2-20-GOOR | 20 (40 μL) | 200 μL |
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| LETM2-ERCC2-20-GOGO | 20 (40 μL) | 200 μL |
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| LETM2-ERCC2-20-GOGR | 20 (40 μL) | 200 μL |
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| LETM2-ERCC2-20-GOAQ | 20 (40 μL) | 200 μL |
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| LETM2-ERCC2-20-GRRE | 20 (40 μL) | 200 μL |
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| LETM2-ERCC2-20-GROR | 20 (40 μL) | 200 μL |
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| LETM2-ERCC2-20-GRGO | 20 (40 μL) | 200 μL |
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| LETM2-ERCC2-20-GRGR | 20 (40 μL) | 200 μL |
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| LETM2-ERCC2-20-GRAQ | 20 (40 μL) | 200 μL |
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| LETM2-ERCC2-20-AQRE | 20 (40 μL) | 200 μL |
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| LETM2-ERCC2-20-AQOR | 20 (40 μL) | 200 μL |
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| LETM2-ERCC2-20-AQGO | 20 (40 μL) | 200 μL |
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| LETM2-ERCC2-20-AQGR | 20 (40 μL) | 200 μL |
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| LETM2-ERCC2-20-AQAQ | 20 (40 μL) | 200 μL |
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ERCC2 Gene Summary
The nucleotide excision repair pathway is a mechanism to repair damage to DNA. The protein encoded by this gene is involved in transcription-coupled nucleotide excision repair and is an integral member of the basal transcription factor BTF2/TFIIH complex. The gene product has ATP-dependent DNA helicase activity and belongs to the RAD3/XPD subfamily of helicases. Defects in this gene can result in three different disorders, the cancer-prone syndrome xeroderma pigmentosum complementation group D, trichothiodystrophy, and Cockayne syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]
Gene Name: ERCC Excision Repair 2, TFIIH Core Complex Helicase Subunit
Chromosome: CHR19: 45854648 -45873845
Locus: 19q13.32
LETM2 Gene Summary
The Leucine Zipper And EF-hand Containing Transmembrane Protein 2 (LETM2) gene is located on chr8 :38243958-38266062 at 8p11.23.
Gene Name: Leucine Zipper And EF-hand Containing Transmembrane Protein 2
Chromosome: CHR8: 38243958 -38266062
Locus: 8p11.23
Gene Diseases
The LETM2 ERCC2 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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