LGALS13-PTPRH Fusion FISH Probe
The LGALS13-PTPRH Fusion FISH Probe is used to confirm a fusion of the LGALS13 and PTPRH genes. The fusion of the LGALS13 and PTPRH genes has been associated with Brain Lower Grade Glioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| LGALS13-PTPRH-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| LGALS13-PTPRH-20-RERE | 20 (40 μL) | 200 μL |
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| LGALS13-PTPRH-20-REOR | 20 (40 μL) | 200 μL |
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| LGALS13-PTPRH-20-REGO | 20 (40 μL) | 200 μL |
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| LGALS13-PTPRH-20-REGR | 20 (40 μL) | 200 μL |
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| LGALS13-PTPRH-20-REAQ | 20 (40 μL) | 200 μL |
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| LGALS13-PTPRH-20-ORRE | 20 (40 μL) | 200 μL |
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| LGALS13-PTPRH-20-OROR | 20 (40 μL) | 200 μL |
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| LGALS13-PTPRH-20-ORGO | 20 (40 μL) | 200 μL |
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| LGALS13-PTPRH-20-ORAQ | 20 (40 μL) | 200 μL |
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| LGALS13-PTPRH-20-GORE | 20 (40 μL) | 200 μL |
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| LGALS13-PTPRH-20-GOOR | 20 (40 μL) | 200 μL |
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| LGALS13-PTPRH-20-GOGO | 20 (40 μL) | 200 μL |
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| LGALS13-PTPRH-20-GOGR | 20 (40 μL) | 200 μL |
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| LGALS13-PTPRH-20-GOAQ | 20 (40 μL) | 200 μL |
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| LGALS13-PTPRH-20-GRRE | 20 (40 μL) | 200 μL |
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| LGALS13-PTPRH-20-GROR | 20 (40 μL) | 200 μL |
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| LGALS13-PTPRH-20-GRGO | 20 (40 μL) | 200 μL |
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| LGALS13-PTPRH-20-GRGR | 20 (40 μL) | 200 μL |
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| LGALS13-PTPRH-20-GRAQ | 20 (40 μL) | 200 μL |
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| LGALS13-PTPRH-20-AQRE | 20 (40 μL) | 200 μL |
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| LGALS13-PTPRH-20-AQOR | 20 (40 μL) | 200 μL |
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| LGALS13-PTPRH-20-AQGO | 20 (40 μL) | 200 μL |
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| LGALS13-PTPRH-20-AQGR | 20 (40 μL) | 200 μL |
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| LGALS13-PTPRH-20-AQAQ | 20 (40 μL) | 200 μL |
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PTPRH Gene Summary
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single intracytoplasmic catalytic domain, and thus represents a receptor-type PTP. The extracellular region contains eight fibronectin type III-like repeats and multiple N-glycosylation sites. The gene was shown to be expressed primarily in brain and liver, and at a lower level in heart and stomach. It was also found to be expressed in several cancer cell lines, but not in the corresponding normal tissues. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2009]
Gene Name: Protein Tyrosine Phosphatase, Receptor Type H
Chromosome: CHR19: 55692614 -55720874
Locus: 19q13.42
LGALS13 Gene Summary
Lysophospholipases are enzymes that act on biological membranes to regulate the multifunctional lysophospholipids. The protein encoded by this gene has lysophospholipase activity. It is composed of two identical subunits which are held together by disulfide bonds. This protein has structural similarity to several members of the beta-galactoside-binding S-type lectin family. [provided by RefSeq, Jul 2008]
Gene Name: Galectin 13
Chromosome: CHR19: 40093168 -40098114
Locus: 19q13.2
Gene Diseases
The LGALS13 PTPRH Fusion has been associated with the following diseases:
| Disease Name |
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| Brain Lower Grade Glioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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