LGALS3BP-CLSPN Fusion FISH Probe
The LGALS3BP-CLSPN Fusion FISH Probe is used to confirm a fusion of the LGALS3BP and CLSPN genes. The fusion of the LGALS3BP and CLSPN genes has been associated with Cervical Squamous Cell Carcinoma And Endocervical Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| LGALS3BP-CLSPN-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| LGALS3BP-CLSPN-20-RERE | 20 (40 μL) | 200 μL |
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| LGALS3BP-CLSPN-20-REOR | 20 (40 μL) | 200 μL |
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| LGALS3BP-CLSPN-20-REGO | 20 (40 μL) | 200 μL |
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| LGALS3BP-CLSPN-20-REGR | 20 (40 μL) | 200 μL |
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| LGALS3BP-CLSPN-20-REAQ | 20 (40 μL) | 200 μL |
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| LGALS3BP-CLSPN-20-ORRE | 20 (40 μL) | 200 μL |
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| LGALS3BP-CLSPN-20-OROR | 20 (40 μL) | 200 μL |
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| LGALS3BP-CLSPN-20-ORGO | 20 (40 μL) | 200 μL |
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| LGALS3BP-CLSPN-20-ORAQ | 20 (40 μL) | 200 μL |
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| LGALS3BP-CLSPN-20-GORE | 20 (40 μL) | 200 μL |
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| LGALS3BP-CLSPN-20-GOOR | 20 (40 μL) | 200 μL |
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| LGALS3BP-CLSPN-20-GOGO | 20 (40 μL) | 200 μL |
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| LGALS3BP-CLSPN-20-GOGR | 20 (40 μL) | 200 μL |
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| LGALS3BP-CLSPN-20-GOAQ | 20 (40 μL) | 200 μL |
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| LGALS3BP-CLSPN-20-GRRE | 20 (40 μL) | 200 μL |
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| LGALS3BP-CLSPN-20-GROR | 20 (40 μL) | 200 μL |
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| LGALS3BP-CLSPN-20-GRGO | 20 (40 μL) | 200 μL |
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| LGALS3BP-CLSPN-20-GRGR | 20 (40 μL) | 200 μL |
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| LGALS3BP-CLSPN-20-GRAQ | 20 (40 μL) | 200 μL |
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| LGALS3BP-CLSPN-20-AQRE | 20 (40 μL) | 200 μL |
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| LGALS3BP-CLSPN-20-AQOR | 20 (40 μL) | 200 μL |
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| LGALS3BP-CLSPN-20-AQGO | 20 (40 μL) | 200 μL |
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| LGALS3BP-CLSPN-20-AQGR | 20 (40 μL) | 200 μL |
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| LGALS3BP-CLSPN-20-AQAQ | 20 (40 μL) | 200 μL |
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LGALS3BP Gene Summary
The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. LGALS3BP has been found elevated in the serum of patients with cancer and in those infected by the human immunodeficiency virus (HIV). It appears to be implicated in immune response associated with natural killer (NK) and lymphokine-activated killer (LAK) cell cytotoxicity. Using fluorescence in situ hybridization the full length 90K cDNA has been localized to chromosome 17q25. The native protein binds specifically to a human macrophage-associated lectin known as Mac-2 and also binds galectin 1. [provided by RefSeq, Jul 2008]
Gene Name: Galectin 3 Binding Protein
Chromosome: CHR17: 76967334 -76976061
Locus: 17q25.3
CLSPN Gene Summary
The product of this gene is an essential upstream regulator of checkpoint kinase 1 and triggers a checkpoint arrest of the cell cycle in response to replicative stress or DNA damage. The protein is also required for efficient DNA replication during a normal S phase. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010]
Gene Name: Claspin
Chromosome: CHR1: 36197712 -36235551
Locus: 1p34.3
Gene Diseases
The LGALS3BP CLSPN Fusion has been associated with the following diseases:
| Disease Name |
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| Cervical Squamous Cell Carcinoma And Endocervical Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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