LHFPL2-HIST1H2AC Fusion FISH Probe
The LHFPL2-HIST1H2AC Fusion FISH Probe is used to confirm a fusion of the LHFPL2 and HIST1H2AC genes. The fusion of the LHFPL2 and HIST1H2AC genes has been associated with Kidney Renal Clear Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| LHFPL2-HIST1H2AC-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| LHFPL2-HIST1H2AC-20-RERE | 20 (40 μL) | 200 μL |
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| LHFPL2-HIST1H2AC-20-REOR | 20 (40 μL) | 200 μL |
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| LHFPL2-HIST1H2AC-20-REGO | 20 (40 μL) | 200 μL |
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| LHFPL2-HIST1H2AC-20-REGR | 20 (40 μL) | 200 μL |
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| LHFPL2-HIST1H2AC-20-REAQ | 20 (40 μL) | 200 μL |
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| LHFPL2-HIST1H2AC-20-ORRE | 20 (40 μL) | 200 μL |
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| LHFPL2-HIST1H2AC-20-OROR | 20 (40 μL) | 200 μL |
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| LHFPL2-HIST1H2AC-20-ORGO | 20 (40 μL) | 200 μL |
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| LHFPL2-HIST1H2AC-20-ORAQ | 20 (40 μL) | 200 μL |
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| LHFPL2-HIST1H2AC-20-GORE | 20 (40 μL) | 200 μL |
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| LHFPL2-HIST1H2AC-20-GOOR | 20 (40 μL) | 200 μL |
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| LHFPL2-HIST1H2AC-20-GOGO | 20 (40 μL) | 200 μL |
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| LHFPL2-HIST1H2AC-20-GOGR | 20 (40 μL) | 200 μL |
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| LHFPL2-HIST1H2AC-20-GOAQ | 20 (40 μL) | 200 μL |
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| LHFPL2-HIST1H2AC-20-GRRE | 20 (40 μL) | 200 μL |
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| LHFPL2-HIST1H2AC-20-GROR | 20 (40 μL) | 200 μL |
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| LHFPL2-HIST1H2AC-20-GRGO | 20 (40 μL) | 200 μL |
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| LHFPL2-HIST1H2AC-20-GRGR | 20 (40 μL) | 200 μL |
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| LHFPL2-HIST1H2AC-20-GRAQ | 20 (40 μL) | 200 μL |
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| LHFPL2-HIST1H2AC-20-AQRE | 20 (40 μL) | 200 μL |
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| LHFPL2-HIST1H2AC-20-AQOR | 20 (40 μL) | 200 μL |
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| LHFPL2-HIST1H2AC-20-AQGO | 20 (40 μL) | 200 μL |
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| LHFPL2-HIST1H2AC-20-AQGR | 20 (40 μL) | 200 μL |
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| LHFPL2-HIST1H2AC-20-AQAQ | 20 (40 μL) | 200 μL |
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HIST1H2AC Gene Summary
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2A family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6. [provided by RefSeq, Aug 2015]
Gene Name: Histone Cluster 1 H2A Family Member C
Chromosome: CHR6: 26124372 -26124918
Locus: 6p22.2
LHFPL2 Gene Summary
This gene is a member of the lipoma HMGIC fusion partner (LHFP) gene family, which is a subset of the superfamily of tetraspan transmembrane protein encoding genes. Mutations in one LHFP-like gene result in deafness in humans and mice, and a second LHFP-like gene is fused to a high-mobility group gene in a translocation-associated lipoma. Alternatively spliced transcript variants have been found, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
Gene Name: LHFPL Tetraspan Subfamily Member 2
Chromosome: CHR5: 77781037 -77944648
Locus: 5q14.1
Gene Diseases
The LHFPL2 HIST1H2AC Fusion has been associated with the following diseases:
| Disease Name |
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| Kidney Renal Clear Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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