LIFR-BCAS3 Fusion FISH Probe
The LIFR-BCAS3 Fusion FISH Probe is used to confirm a fusion of the LIFR and BCAS3 genes. The fusion of the LIFR and BCAS3 genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| LIFR-BCAS3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| LIFR-BCAS3-20-RERE | 20 (40 μL) | 200 μL |
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| LIFR-BCAS3-20-REOR | 20 (40 μL) | 200 μL |
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| LIFR-BCAS3-20-REGO | 20 (40 μL) | 200 μL |
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| LIFR-BCAS3-20-REGR | 20 (40 μL) | 200 μL |
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| LIFR-BCAS3-20-REAQ | 20 (40 μL) | 200 μL |
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| LIFR-BCAS3-20-ORRE | 20 (40 μL) | 200 μL |
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| LIFR-BCAS3-20-OROR | 20 (40 μL) | 200 μL |
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| LIFR-BCAS3-20-ORGO | 20 (40 μL) | 200 μL |
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| LIFR-BCAS3-20-ORAQ | 20 (40 μL) | 200 μL |
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| LIFR-BCAS3-20-GORE | 20 (40 μL) | 200 μL |
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| LIFR-BCAS3-20-GOOR | 20 (40 μL) | 200 μL |
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| LIFR-BCAS3-20-GOGO | 20 (40 μL) | 200 μL |
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| LIFR-BCAS3-20-GOGR | 20 (40 μL) | 200 μL |
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| LIFR-BCAS3-20-GOAQ | 20 (40 μL) | 200 μL |
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| LIFR-BCAS3-20-GRRE | 20 (40 μL) | 200 μL |
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| LIFR-BCAS3-20-GROR | 20 (40 μL) | 200 μL |
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| LIFR-BCAS3-20-GRGO | 20 (40 μL) | 200 μL |
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| LIFR-BCAS3-20-GRGR | 20 (40 μL) | 200 μL |
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| LIFR-BCAS3-20-GRAQ | 20 (40 μL) | 200 μL |
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| LIFR-BCAS3-20-AQRE | 20 (40 μL) | 200 μL |
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| LIFR-BCAS3-20-AQOR | 20 (40 μL) | 200 μL |
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| LIFR-BCAS3-20-AQGO | 20 (40 μL) | 200 μL |
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| LIFR-BCAS3-20-AQGR | 20 (40 μL) | 200 μL |
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| LIFR-BCAS3-20-AQAQ | 20 (40 μL) | 200 μL |
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LIFR Gene Summary
This gene encodes a protein that belongs to the type I cytokine receptor family. This protein combines with a high-affinity converter subunit, gp130, to form a receptor complex that mediates the action of the leukemia inhibitory factor, a polyfunctional cytokine that is involved in cellular differentiation, proliferation and survival in the adult and the embryo. Mutations in this gene cause Schwartz-Jampel syndrome type 2, a disease belonging to the group of the bent-bone dysplasias. A translocation that involves the promoter of this gene, t(5;8)(p13;q12) with the pleiomorphic adenoma gene 1, is associated with salivary gland pleiomorphic adenoma, a common type of benign epithelial tumor of the salivary gland. Multiple splice variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: LIF Receptor Alpha
Chromosome: CHR5: 38475064 -38595507
Locus: 5p13.1
BCAS3 Gene Summary
The BCAS3, Microtubule Associated Cell Migration Factor (BCAS3) gene is located on chr17 :58755171-59470199 at 17q23.2.
Gene Name: BCAS3, Microtubule Associated Cell Migration Factor
Chromosome: CHR17: 58755171 -59470199
Locus: 17q23.2
Gene Diseases
The LIFR BCAS3 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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