LIMA1-TAOK3 Fusion FISH Probe
The LIMA1-TAOK3 Fusion FISH Probe is used to confirm a fusion of the LIMA1 and TAOK3 genes. The fusion of the LIMA1 and TAOK3 genes has been associated with Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| LIMA1-TAOK3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| LIMA1-TAOK3-20-RERE | 20 (40 μL) | 200 μL |
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| LIMA1-TAOK3-20-REOR | 20 (40 μL) | 200 μL |
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| LIMA1-TAOK3-20-REGO | 20 (40 μL) | 200 μL |
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| LIMA1-TAOK3-20-REGR | 20 (40 μL) | 200 μL |
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| LIMA1-TAOK3-20-REAQ | 20 (40 μL) | 200 μL |
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| LIMA1-TAOK3-20-ORRE | 20 (40 μL) | 200 μL |
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| LIMA1-TAOK3-20-OROR | 20 (40 μL) | 200 μL |
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| LIMA1-TAOK3-20-ORGO | 20 (40 μL) | 200 μL |
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| LIMA1-TAOK3-20-ORAQ | 20 (40 μL) | 200 μL |
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| LIMA1-TAOK3-20-GORE | 20 (40 μL) | 200 μL |
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| LIMA1-TAOK3-20-GOOR | 20 (40 μL) | 200 μL |
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| LIMA1-TAOK3-20-GOGO | 20 (40 μL) | 200 μL |
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| LIMA1-TAOK3-20-GOGR | 20 (40 μL) | 200 μL |
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| LIMA1-TAOK3-20-GOAQ | 20 (40 μL) | 200 μL |
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| LIMA1-TAOK3-20-GRRE | 20 (40 μL) | 200 μL |
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| LIMA1-TAOK3-20-GROR | 20 (40 μL) | 200 μL |
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| LIMA1-TAOK3-20-GRGO | 20 (40 μL) | 200 μL |
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| LIMA1-TAOK3-20-GRGR | 20 (40 μL) | 200 μL |
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| LIMA1-TAOK3-20-GRAQ | 20 (40 μL) | 200 μL |
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| LIMA1-TAOK3-20-AQRE | 20 (40 μL) | 200 μL |
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| LIMA1-TAOK3-20-AQOR | 20 (40 μL) | 200 μL |
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| LIMA1-TAOK3-20-AQGO | 20 (40 μL) | 200 μL |
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| LIMA1-TAOK3-20-AQGR | 20 (40 μL) | 200 μL |
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| LIMA1-TAOK3-20-AQAQ | 20 (40 μL) | 200 μL |
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TAOK3 Gene Summary
The protein encoded by this gene is a serine/threonine protein kinase that activates the p38/MAPK14 stress-activated MAPK cascade but inhibits the basal activity of the MAPK8/JNK cascade. The encoded protein is a member of the GCK subfamily of STE20-like kinases. [provided by RefSeq, Oct 2016]
Gene Name: TAO Kinase 3
Chromosome: CHR12: 118587605 -118810750
Locus: 12q24.23
LIMA1 Gene Summary
This gene encodes a cytoskeleton-associated protein that inhibits actin filament depolymerization and cross-links filaments in bundles. It is downregulated in some cancer cell lines. Alternatively spliced transcript variants encoding different isoforms have been described for this gene, and expression of some of the variants maybe independently regulated. [provided by RefSeq, Aug 2011]
Gene Name: LIM Domain And Actin Binding 1
Chromosome: CHR12: 50569562 -50677353
Locus: 12q13.12
Gene Diseases
The LIMA1 TAOK3 Fusion has been associated with the following diseases:
| Disease Name |
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| Bladder Urothelial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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